Kavalactones
Source: Dried root or rhizome of the pepper plant Piper methysticum
Latin Name: Piper methysticum Forst.
Testing Method: HPLC
Purity: ≥30%
Active Ingredients: Primarily six core kavalactone compounds, including kavain, dihydrokavain, methysticin, yangonin, etc.
Appearance: Light yellow to yellow powder
Grade: Commonly food grade/raw material for health products
Brand: Tihealth
Packaging: 1 kg/bottle & bag; 25 kg/drum & bag (customizable)
Storage Method: Store in a dry, cool place, protected from direct sunlight and high temperatures. Recommended storage conditions: temperature ≤25°C, humidity ≤60%.
Shelf Life: 24 months
Kava Extract Powder | Standardized Kavalactones | Relaxant API
Kava Extract (derived from Piper methysticum) is globally recognized for its profound anxiolytic (anti-anxiety) and muscle-relaxing properties without diminishing cognitive clarity. Xi'an Tihealth Biotechnology Co., Ltd. strictly sources noble Kava lateral roots (bypassing toxic peel and stem materials) to produce a highly purified, standardized extract. Utilizing advanced solvent extraction, we guarantee precise concentrations of 30.0% to 70.0% Kavalactones (via HPLC). This premium botanical API is the foundational ingredient for modern stress-relief supplements, sleep-aid capsules, and relaxation functional beverages.
Technical Specifications & Quality Metrics
| Analytical Parameter | Xi'an Tihealth Specification |
|---|---|
| Botanical Source | Piper methysticum (Noble Kava Lateral Roots Only) |
| Standardized Active | Total Kavalactones ≥ 30.0%, 50.0%, 70.0% (HPLC) |
| Extraction Solvent | Ethanol / Water (Strictly non-acetone/non-hexane processing) |
| Appearance | Light yellow to brownish-yellow fine powder |
| Pharmacological Target | GABA-A Receptor Modulation; Non-narcotic muscle relaxation |
GABAergic Modulation & Anxiolytic Mechanisms
- GABA-A Receptor Synergy: Kavalactones (including Kavain, Dihydrokavain, and Methysticin) do not directly bind to GABA receptors like synthetic benzodiazepines. Instead, they modulate the receptor's affinity, enhancing the natural calming effect of endogenous GABA without causing severe sedation or chemical dependency.
- Limbic System Targeting: The lipophilic nature of Kavalactones allows them to easily cross the blood-brain barrier. They actively reduce excitability in the amygdala (the brain's fear/anxiety center), providing rapid relief from acute psychological stress.
- Skeletal Muscle Relaxation: Beyond central nervous system effects, Kavalactones decrease muscle spasticity by blocking voltage-gated sodium and calcium channels, aiding in physical tension relief and improving deep sleep architecture.
Formulator & Procurement FAQ
Historical concerns regarding Kava liver toxicity were traced to the unethical use of aerial parts (stems/peel) and the use of harsh industrial solvents like acetone. We strictly utilize only the peeled lateral roots of Noble Kava varieties and extract them using safe, food-grade Ethanol and water. This entirely eliminates the toxic alkaloid 'Pipermethystine' from our finished extract.
No. Kavalactones are highly lipophilic (fat-soluble) resins. Our 70% extract is ideal for dry capsule filling, tinctures (ethanol base), and softgel suspensions. If you require a water-dispersible version for "chill drinks" or teas, please inquire about our specialized 30% Water-Dispersible Kava powder.
Xi'an Tihealth Biotechnology Co., Ltd. Quality Commitment: Standardized botanical extract intended for commercial dietary supplement and nutraceutical manufacturing. Always formulate in compliance with local market regulations.
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