Sclareol Extract

Sclareol Extract

Product Name:Sclareol extract
Plant Source:Derived from the flower clusters and leaves of Salvia sclarea L. (commonly known as clary sage or South European sage).
CAS Number:515-03-7
Product Specification:Sclareol 98%
Detection Method:Gas Chromatography (GC)
Product Characteristics:A white crystalline powder with a melting point of 95-105°C. It has a scent reminiscent of ambergris, characterized by a delicate, strong, and long-lasting aroma that contributes a vibrant and harmonious fragrance to perfumes.
Screening:95% through 80 mesh
Packaging Specifications: 25 kg per cardboard drum ;1 kg per aluminum foil bag
Storage Conditions:Store in a sealed, cool, moisture-proof, and light-protected environment.
Shelf Life:24 months.
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Products Description

 

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Pharmaceutical & Fragrance Grade Sclareol (≥98%)
by Xi'an Tihealth

Xi'an Tihealth Biotechnology Co., Ltd. is a specialized global B2B manufacturer of high-purity Sclareol Extract. Sourced from the natural inflorescences and leaves of premium Clary Sage (Salvia sclarea L.), our Sclareol is isolated using an advanced low-temperature solvent extraction and multi-stage crystallization process.

Standardized to an ultra-high purity of ≥ 98.0% (HPLC), our Sclareol presents as a pristine white crystalline powder. It is internationally recognized as the premier, sustainable botanical precursor for the synthesis of Ambroxide (Ambroxan)-a highly valued ambergris substitute in the fine perfumery industry. Beyond its critical role in fragrance synthesis, it serves as an excellent natural fixative and exhibits potent antimicrobial properties for dermatological and cosmetic applications. Manufactured under strict ISO and GMP protocols, we guarantee consistent batch-to-batch quality and ultra-low solvent residues.

 

Technical Data Sheet (TDS) & COA Profile

 

Test Item Specification Result (Batch: TK-SCL-20240820) Test Method
Botanical Source Salvia sclarea L. (Clary Sage) Complies Macroscopic
Purity (Sclareol Assay) ≥ 98.0% 98.2% HPLC (USP <621>)
CAS Number 515-03-7 - -
Appearance White crystalline powder White Visual
Moisture & Residue ≤ 0.5% / ≤ 0.1% 0.23% / 0.05% Karl Fischer / USP <281>
Residual Solvents ≤ 3000 ppm < 50 ppm GC-FID
Heavy Metals (Pb, As, Cd, Hg) Complies with limits Not Detected / < Limits ICP-MS
Total Plate Count ≤ 1000 CFU/g < 100 CFU/g USP <61>

 

Proprietary B2B Advantages

1. High-Yield Ambroxide Precursor

For fragrance and flavor manufacturers, the starting purity of Sclareol directly dictates the synthetic yield of Ambroxide. Our rigorous multi-stage crystallization process guarantees a consistent ≥98% purity, providing chemical engineers with a highly stable and predictable precursor for high-yield bioconversion.

2. Strict Solvent Control (<50 ppm)

Traditional extraction processes often leave high levels of residual extraction solvents (200-1000 ppm) which can ruin the olfactory profile of fine perfumes. Tihealth's low-temperature purification technology strictly controls solvent residues to under 50 ppm, ensuring zero interference with delicate fragrance notes.

3. Sustainable Botanical Sourcing

Harvested from dedicated, pollution-free Clary Sage cultivation bases. This ensures an eco-friendly and cruelty-free alternative to animal-derived ambergris, aligning perfectly with the modern fragrance industry's shift towards sustainable, vegan, and clean-label ingredients.

 

Industrial & Dermatological Functions

 

The core applications of Sclareol are driven by its unique bicyclic diterpene alcohol structure:

1. Ambroxide Synthesis Base

The primary industrial use. Sclareol is oxidized and cyclized to synthesize Ambroxide (Ambroxan), the most crucial and expensive ambergris substitute used in luxury perfumes.

2. Natural Fragrance Fixative

Acts as a powerful fixative in the perfumery sector. Its delicate, woody-amber olfactory profile anchors highly volatile top notes, extending fragrance longevity by up to 8 hours.

3. Potent Antimicrobial

Exhibits strong inhibitory effects against various pathogens, including Staphylococcus aureus and acne-causing bacteria, making it highly valuable for dermatological formulations.

4. Skin Soothing & Repair

Demonstrates significant anti-inflammatory activity. It promotes lipid synthesis in the stratum corneum, effectively alleviating dryness and reducing redness in sensitive skin.

5. Aromatherapy & Wellness

The subtle aromatic profile of Sclareol is utilized in premium home fragrances and pet care to alleviate stress and anxiety through olfactory neural pathways.

6. Agricultural Biocontrol

Research indicates Sclareol interferes with the adhesion of specific plant pathogens, presenting potential as an eco-friendly botanical biopesticide.

 

Industrial Formulation Applications

 

Fine Fragrances & Flavors

The critical API for chemical companies synthesizing Ambroxide, and a direct natural fixative used by international perfume houses to enhance scent longevity.

Premium Cosmeceuticals

Formulated into anti-acne serums and skin-soothing creams due to its rapid antimicrobial action and ability to repair damaged lipid barriers.

Aromatherapy & Home Care

Utilized as a high-end botanical active in essential oil blends, premium reed diffusers, and luxury pet grooming products.

Pharmaceutical R&D

Serves as a reliable, standardized diterpene framework for medicinal chemistry research focusing on novel anti-inflammatory and antiviral therapies.

 

Advanced Production Process

 

Tihealth's extraction protocol focuses on precise low-temperature solvent extraction and intensive crystallization to protect the delicate diterpene structure.

01

Botanical Sourcing & Prep

Freshly harvested Clary Sage (Salvia sclarea) inflorescences and leaves are dried under controlled conditions to preserve the essential volatile oils.

02

Low-Temp Solvent Extraction

The biomass undergoes extraction at 30-40°C. This avoids the 30-50% activity loss commonly seen in traditional high-heat (60-80°C) extraction methods.

03

Dewaxing & Purification

The crude extract is subjected to winterization (cooling) to precipitate and remove heavy plant waxes and inactive lipids.

04

Multi-Stage Crystallization

Through precise solvent recovery and multi-stage crystallization, the Sclareol precipitates into highly pure (≥98%) white crystals, leaving impurities behind.

05

Vacuum Drying & QA

The crystals are vacuum-dried and analytically verified via HPLC. Residual solvents are strictly monitored via GC-FID to ensure levels remain <50 ppm.

 

 

Packing, Logistics, Payment

 

 

 

Packaging Global Supply Chain Delivery
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Payment Methods
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Formulator & Procurement FAQ

01. Is your Sclareol suitable for synthesizing Ambroxide?

Yes, absolutely. With a guaranteed purity of ≥ 98.0%, our crystalline Sclareol is the ideal, highly stable starting material for chemical and biological conversion into Ambroxide (Ambroxan). The ultra-low impurity profile ensures maximum synthetic yield for fragrance manufacturers.

02. How do you manage solvent residues, given its use in perfumery?

We understand that trace solvents can entirely ruin a fragrance's olfactory profile. Through our proprietary multi-stage crystallization and vacuum drying process, we strictly cap solvent residues at under 50 ppm-far below the standard regulatory limits.

03. Is the botanical source Perilla or Clary Sage?

It is exclusively extracted from Clary Sage (Salvia sclarea L.). Please note that some generic market translations incorrectly list "Perilla" (which is a completely different plant). We provide full botanical traceability to certify authentic Clary Sage sourcing.

04. What is the Minimum Order Quantity (MOQ) and lead time?

Our standard MOQ is 1kg (packaged in an aluminum foil bag) to support R&D trials. For bulk commercial orders (25kg cardboard drums), our lead time is typically within 15 days. We are fully equipped to supply large-scale contract orders for multinational fragrance houses.

 

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