Liquid Sophora Flavescens
Source: Sophora flavescens plant
Specification: 5%,10%, 98%
Samples: Could be offered
Color: Dark brown or brownish yellow liquid
Product storage: Keep in a cool, dry, dark, and high-temperature place
Shelf life: Two years
Industrial-Grade Sophora Flavescens Liquid Extract (Ku Shen)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a specialized global B2B manufacturer of high-quality Sophora Flavescens Liquid Extract (Ku Shen Extract). We rigorously source from the premium, heavy-metal-free dried roots of Sophora flavescens Aiton. Utilizing advanced low-temperature ultrasonic-assisted extraction combined with precision molecular membrane separation, we effectively capture and concentrate the plant's complete spectrum of active quinolizidine alkaloids while stripping away irritating botanical impurities.
Our standardized liquid is highly concentrated, guaranteeing a potent yield of Total Alkaloids (primarily Matrine and Oxymatrine) between 1.2% and 2.0% via HPLC, alongside synergistic flavonoids. Exhibiting superior broad-spectrum antimicrobial, potent anti-inflammatory, and remarkable biopesticidal properties, this clear, weakly acidic botanical liquid integrates seamlessly into aqueous formulations. It is an indispensable, highly cost-effective raw material for advanced gynecological washes, dermatological repair lotions, clinical veterinary medicines, and zero-residue botanical agrochemicals.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Dried roots of Sophora flavescens Aiton | Verified | Macroscopic ID |
| Total Alkaloids (Matrine & Oxymatrine) | ≥ 1.2% - 1.5% (Custom to 2.0%) | 1.35% | HPLC |
| Appearance | Dark brown to brownish-yellow clear liquid | Complies | Visual Assessment |
| pH Value | 4.0 - 6.5 (Weakly acidic profile) | 5.2 | pH Meter |
| Solubility | Miscible with water and ethanol | Complies | Aqueous Dispersion |
| Heavy Metals (Pb, As) | ≤ 10.0 ppm / ≤ 2.0 ppm | < 5.0 ppm / < 0.5 ppm | ICP-MS |
| Microbiology (Total Plate) | ≤ 1000 CFU/ml | < 100 CFU/ml | USP <61> |
Manufacturing & Processing Excellence
Low-Temp Ultrasonic Cavitation
Standard high-heat decoctions destroy delicate active compounds and yield turbid liquids. Tihealth employs low-temperature, ultrasonic-assisted cavitation. This effectively disrupts the rigid root cellular matrices without thermal degradation, ensuring a highly concentrated Matrine and Oxymatrine yield that guarantees rapid clinical and cosmetic efficacy.
Advanced Membrane Separation
Unlike rudimentary liquid extracts that cause severe dermal irritation and nozzle clogging, we utilize precision molecular membrane filtration. This critical step strips away macromolecular plant debris, heavy waxes, and residual tannins (achieving >98% impurity removal), resulting in a clear, hypoallergenic liquid optimized for direct topical formulation.
Targeted Pathogen Optimization
Our alkaloid profile is chemically standardized to target over 12 common pathogenic strains (including aggressive Candida albicans, Streptococcus hemolyticus, and agricultural Pseudomonas). This verifiable broad-spectrum efficacy makes our extract vastly superior to single-target or non-standardized botanical washes.
Evidence-Based Pharmacological Mechanisms
Gynecological & Dermatological Regulation
Matrine and Oxymatrine exhibit profound broad-spectrum antimicrobial and antifungal activity. When applied topically, the extract rapidly denatures the cell membranes of pathogens, providing potent, non-steroidal relief for Trichomonas vaginitis, severe dermal eczema, and intense pruritus without disrupting the natural localized microbiome.
Cellular Anti-Inflammatory & Analgesic
Demonstrates significant analgesic effects by directly suppressing localized tissue inflammation. It inhibits the release of pro-inflammatory cytokines, stabilizing capillary permeability in cases involving mucosal damage, making it highly effective for post-operative clinical repair washes.
Oncology Adjuvant & Antiviral Support
In advanced clinical R&D, the isolated alkaloids are extensively researched for their ability to induce cellular apoptosis and inhibit abnormal tumor proliferation. Furthermore, Oxymatrine is utilized in therapeutic protocols for its demonstrated antiviral capabilities against Hepatitis B (HBV) and Coxsackievirus.
Eco-Friendly Biopesticidal Action
In agricultural applications, Matrine functions as a highly effective neurotoxin to insects and a potent botanical fungicide. It paralyzes the central nervous system of agricultural pests upon contact, offering a zero-residue, highly degradable alternative to toxic synthetic organophosphates.
Industrial Formulation Applications
Gynecological & Clinical Care
The primary botanical API for formulating hospital-grade feminine washes, topical anti-pruritic lotions, and suppositories addressing severe vaginal infections and eczema.
Botanical Biopesticides
A highly effective, eco-friendly green pesticide. Formulated into agricultural sprays, it acts as a natural insecticide and fungicide, safely replacing toxic synthetic chemicals without soil accumulation.
Veterinary Health Products
Because it is fully water-soluble and non-toxic to mammals, it is heavily utilized in veterinary dips and sprays to eradicate ectoparasites, mites, and stubborn fungal infections in livestock.
Pharmaceutical Antiviral Therapies
Leveraged extensively in pharmaceutical R&D for its demonstrated antiviral and hepatoprotective capabilities, particularly as a foundational ingredient in anti-Hepatitis B (HBV) therapeutic protocols.
Contract Manufacturing & Global Supply Chain
♦ Precise Active Customization
We strictly tailor the concentration of Total Alkaloids (typically 1.2% to 1.5%, up to custom 2.0% HPLC specs) to perfectly match your specific formulation requirements, whether for highly sensitive cosmetic lotions or robust agricultural biopesticides.
♦ Traceable Quality Control
Quality is mathematically verifiable. Every batch undergoes strict cGMP-certified analysis via HPLC. We provide full COAs, ensuring heavy metals, pathogens, and residual moisture strictly comply with global pharmaceutical and cosmetic safety standards.
♦ Secure Export Bulk Fulfillment
We specialize in liquid extraction logistics. We offer blind shipping, bulk HDPE drum packaging (25kg to 200kg IBC totes), and full FDA/EU regulatory documentation support for rapid global customs clearance without leakage risks.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide industrial-grade HDPE liquid packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, leakage-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. Can this liquid extract be directly formulated into biopesticides?
Yes. Our Sophora Flavescens Liquid (Matrine content) acts as an excellent, broad-spectrum botanical insecticide and fungicide. It is completely biodegradable, leaves no toxic residue, and is highly suitable for organic farming formulations.
02. What is the difference between the Liquid Extract and Powder API?
The liquid extract (typically 1.2% - 2% Matrine) preserves the natural synergistic flavonoids and is cost-effective for direct blending into lotions, shampoos, and agricultural sprays without heating. The powder form (up to 98% Matrine) is an isolated API used for precise capsule or tablet manufacturing.
03. Does the liquid contain heavy plant waxes that clog agricultural spray nozzles?
No. Our advanced molecular membrane filtration process specifically targets and strips away large plant proteins, inert fibers, and heavy waxes. This guarantees a clean, low-viscosity liquid that flows flawlessly through cosmetic pumps and micro-agricultural spray nozzles.
04. How is the liquid packaged for bulk international shipping?
Bulk liquid extracts are securely packaged in food-grade, high-density polyethylene (HDPE) drums (e.g., 25kg or 200kg IBC totes) to prevent leakage and photodegradation during air or sea freight. All containers are sealed with tamper-evident closures.
05. Do you supply Free Samples for R&D testing?
Absolutely. We understand the stringent demands of cosmetic and agrochemical R&D. Tihealth provides 50ml - 100ml free liquid samples along with batch-specific Certificates of Analysis (COA) for your laboratory stability and pH compatibility trials.
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