Ziziphus Jujuba Extract Liquid

Ziziphus jujuba Extract Liquid is a premium botanical extract derived from the mature fruits of Ziziphus jujuba Mill. var. inermis (Bunge) Rehd. using a low-temperature ultrasonic extraction process. Standardized to contain ≥12% jujube polysaccharides and ≥0.8% oleanolic acid, this extract preserves bioactive triterpenoid saponins and volatile oils, aligning with Chinese Pharmacopoeia (ChP 2025) and cGMP guidelines. It is renowned in traditional Chinese medicine (TCM) for its blood-nourishing and spleen-strengthening properties, supported by modern research on immune modulation and hepatoprotection.

Certificate of Analysis

Immune System Support: Polysaccharides act as a powerful immune modulator, significantly enhancing the body's defense mechanisms. In vitro studies have demonstrated a notable 30% increase in the proliferation of CD4+ cells, a critical subset of lymphocytes that coordinates immune responses. These cells play a pivotal role in activating other immune cells, such as B cells and cytotoxic T cells. Additionally, polysaccharides stimulate macrophage phagocytosis, enabling these immune cells to more effectively engulf and eliminate pathogens, damaged cells, and cellular debris, thereby strengthening the body's overall immune resilience.​

Hepatoprotective Activity: Oleanolic acid has shown remarkable hepatoprotective properties, particularly in preclinical models of hepatic injury. Research indicates that it can reduce elevated levels of liver enzymes, alanine transaminase (ALT) and aspartate transaminase (AST), by up to 25%. These enzymes are released into the bloodstream when liver cells are damaged. By decreasing their levels, oleanolic acid helps protect liver cells from further injury, aids in the repair process, and supports the liver's vital functions, including detoxification and metabolism.​

Antioxidant Defense: The formulation exhibits potent antioxidant capabilities, as evidenced by its DPPH radical scavenging activity. With an IC50 value of 32μg/mL, its antioxidant efficacy is comparable to that of vitamin E, a well - known antioxidant. The DPPH assay is a standard method for evaluating a substance's ability to neutralize free radicals. By scavenging harmful free radicals, the formulation helps prevent oxidative damage to cells, protecting cellular components such as lipids, proteins, and DNA from degradation. This antioxidant activity is crucial for maintaining cellular health and reducing the risk of oxidative stress - related diseases.​

Energy Metabolism Regulation: With a long - standing use in Traditional Chinese Medicine (TCM), this formulation has been recognized for its ability to combat fatigue. It achieves this by enhancing glycogen synthesis in muscle tissues. Glycogen serves as a primary energy reserve in muscles, providing a readily available source of glucose during physical activity. By increasing glycogen stores, the formulation supports sustained energy production, reduces muscle fatigue, and improves overall physical performance. This traditional application is now supported by modern scientific understanding of its impact on energy metabolism pathways.​

Raw Material Collection → Low-Temperature Pulverization → Ultrasonic Extraction → Filtration & Chromatography Purification → Vacuum Concentration → Quality Testing → Sterile Packaging → Global Distribution

The OEM services provided by Xi'an Tihealth Biotechnology Co., Ltd. have significant advantages

Customized Formulation

Polysaccharide:Oleanolic Acid ratio optimization

Spray-dried powder (solubility ≥95%) and water-dispersible granules

Regulatory Support:

Technical documentation for FDA NDI, EU CPNP, and TGA submissions.

Stability testing reports

Quality Control: GMP-certified facilities, third-party lab testing for each batch (COA provided).

Brand Confidentiality: White-label solutions with secure IP protection.

Confidentiality Assurance:

Non-disclosure agreements (NDAs) and encrypted formula management

As a biotechnology company, Tihealth Biotechnology Company provides international cross-border e-commerce logistics services with the following characteristics:

1. International express delivery services

2. Dedicated logistics services

3. Support dual clearing service

Q1: Is this extract suitable for vegan products?
A: Yes, it is 100% plant-derived, free from animal ingredients, and certified vegan by the Vegan Society.

Q2: What is the shelf life of the extract?
A: 24 months when stored in unopened original packaging at ≤25℃. Refrigeration (2-8℃) extends shelf life to 36 months.

Q3: Can the extract be used in infant formulas?
A: While generally recognized as safe (GRAS), we recommend consulting a pediatric nutritionist for formulations intended for children under 3 years.

Q4: Does the extraction process use organic solvents?
A: No, we use pure water extraction. Solvent residue levels are below detection limits (<0.01ppm).

Q5: How does your extract differ from competitors?
A: Our proprietary ultrasonic extraction increases polysaccharide yield by 40% compared to traditional methods, while maintaining higher oleanolic acid bioavailability.

Q6: Can I request a COA for regulatory approval?
A: Yes, each batch is accompanied by a detailed COA, MSDS, and third-party lab reports (ISO 17025-accredited).

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