Baicalin Extract
Plant source: Derived from the rhizome of Scutellaria baicalensis, a plant in the family Lamiaceae.
Content specification: 85% -98%
Testing method: HPLC
CAN NO：21967-41-9
Active ingredient: Baicalin
Appearance: Light yellow crystalline powder
Product Usage: Widely used in industries such as video, health products, cosmetics, etc
Product packaging: 1KG/aluminum foil bag; 25KG/cardboard drum
Product storage: Store in a dry and cool place, away from sunlight and high temperatures
Shelf life: 24 months
Product Overview
Pharmaceutical-Grade Scutellaria Baicalensis Extract (Baicalin)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a premier global B2B supplier of highly purified Scutellaria Baicalensis Extract. Derived from the dried roots of the traditional medicinal herb (Chinese Skullcap), our extract is meticulously processed to isolate its most critical bioactive flavone glycoside: Baicalin.
Utilizing advanced water-acid precipitation and ultrasound-assisted extraction (UAE), we achieve exceptional purity levels ranging from 85% to 99%. Distinct from synthetic antimicrobials and corticosteroids, Baicalin acts as a polypharmacological agent, delivering profound broad-spectrum antibacterial, anti-inflammatory, and UV-absorbing properties without cytotoxicity. Our pale-yellow fine powder is a foundational Active Pharmaceutical Ingredient (API) for liver-protection supplements, acne-treatment cosmeceuticals, and natural anti-allergy topical formulations.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Root of Scutellaria baicalensis Georgi | Verified | Macroscopic ID |
| Baicalin Content | ≥ 85.0% to 99.0% | 85.5% (Customizable) | HPLC |
| Appearance | Pale yellow fine powder | Complies | Visual |
| Loss on Drying | ≤ 5.0% | 3.8% | USP <731> |
| Ash Content | ≤ 5.0% | 1.2% | USP <281> |
| Heavy Metals (Pb, As) | ≤ 1.0 ppm / ≤ 0.5 ppm | < 0.5 / < 0.1 | ICP-MS |
| Pesticide Residues | Complies with EP/USP | Not Detected | GC-MS |
| Total Plate Count | ≤ 1000 CFU/g | < 50 CFU/g | ISO 4833-1 |
Manufacturing & Processing Excellence
Targeted Baicalin Enrichment
Through highly optimized water-acid precipitation and sequential recrystallization, we isolate Baicalin with extreme precision. We offer scalable purity gradients from 85% for bulk nutraceuticals up to 99% for rigorous pharmaceutical applications.
pH Resilience & Stability
Our extraction parameters ensure the resulting Baicalin powder exhibits remarkable stability across various pH environments. It retains its potent biological activity whether formulated in acidic cosmetic emulsions or digestive-tract targeted oral tablets.
Eco-Friendly, Non-Toxic Profile
Aligning with green chemistry principles, our extract is entirely plant-derived, biodegradable, and free from phototoxic byproducts. It acts as a highly safe, non-hormonal substitute for synthetic antimicrobials and chemical preservatives.
Evidence-Based Physiological Core Benefits
Broad-Spectrum Antimicrobial Action
Baicalin exhibits potent direct bactericidal effects, particularly against antibiotic-resistant strains (e.g., MRSA) and acne-causing pathogens (Propionibacterium acnes). It helps clear pores and accelerates healing without contributing to antimicrobial resistance.
Profound Anti-Inflammatory & Anti-Allergic Efficacy
Rapidly inhibits the release of pro-inflammatory mediators (prostaglandins and leukotrienes) and blocks histamine receptors. It provides a natural, hormone-free solution to alleviate skin erythema, itching, and atopic sensitivities.
Tyrosinase Inhibition & UV Protection
A highly effective tyrosinase inhibitor, rivaling Vitamin C in its skin-brightening capacity. Additionally, its molecular structure actively absorbs full-spectrum UV radiation (190–400 nm), offering significant photoprotection and mitigating post-sun dermal damage.
Hepatoprotective (Liver Shield)
Acts as a powerful cellular antioxidant. In systemic applications, it significantly alleviates hepatic oxidative stress and liver injury induced by alcohol or hepatotoxic medications.
Industrial Formulation Applications
Pharmaceutical Intermediates
Utilized as an adjunct treatment API in medications targeting hepatitis and chronic infections. In topical formulations, it is a non-irritating base for eczema ointments and oral ulcer gels.
Functional Cosmeceuticals
The "Golden Ingredient" for sensitive-skin repairing serums, anti-acne creams, and botanical sunscreens. It synergizes excellently with niacinamide and hyaluronic acid.
Dietary Supplements & Nutraceuticals
Formulated into antioxidant softgels and liver-protection capsules designed to delay cellular aging, enhance immunity, and mitigate xenobiotic toxicity.
Clean-Label Preservatives
Functions as a natural, plant-derived antimicrobial additive, allowing cosmetics and personal care products to minimize or replace harsh synthetic chemical preservatives.
Contract Manufacturing & Global Supply Chain
♦ Precise Baicalin Customization
We strictly tailor the purity of Baicalin (from 85% to 99% HPLC) to meet your specific therapeutic claims and budgetary requirements for both cosmetic and pharmaceutical lines.
♦ Traceable Quality Control
Every batch undergoes strict cGMP-certified analysis. We provide full COAs, ensuring heavy metals, pathogens, and pesticide residues comply with stringent USP/EP standards.
♦ Strict Brand Confidentiality
Secure IP protection via NDAs. We offer blind shipping, private label bulk packaging (1kg foil bags to 25kg drums), and full FDA/EU regulatory documentation support.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance),
and secure multi-currency payment methods to ensure seamless, oxidation-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. What is the active compound in your Scutellaria baicalensis Extract?
The primary bioactive compound is Baicalin, a naturally occurring flavone glycoside. We utilize HPLC to precisely quantify and standardize its concentration, ensuring you receive a highly potent API.
02. Is it safe for topical cosmetic applications on sensitive skin?
Yes. Baicalin is a non-hormonal, non-toxic botanical extract. It effectively inhibits inflammatory pathways (like histamine release) without the side effects of chemical steroids, making it highly recommended for atopic and sensitive skin formulations.
03. How does Baicalin mitigate antimicrobial resistance?
Baicalin employs dual antimicrobial mechanisms: it exhibits direct bactericidal action against pathogens like MRSA and simultaneously stimulates macrophage-mediated clearance. This complex pathway significantly reduces the likelihood of bacteria developing resistance compared to single-target synthetic antibiotics.
04. Does the extract cause phototoxicity under UV light?
No. On the contrary, Baicalin is highly photostable and acts as a natural UV absorber (190-400 nm). It prevents UV-induced oxidative damage and does not produce any phototoxic byproducts, making it an excellent addition to sunscreens and day creams.
05. What is the Minimum Order Quantity (MOQ) and packaging?
Our standard MOQ for mass production is 25kg, packed in heavy-duty cardboard drums lined with double sterile bags. We also supply 1kg foil bags for pilot manufacturing and R&D formulation trials.
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