Schizonepeta Saponin Extract
Specifications: 50:1&30:1&10:1 or customized according to customer needs
Detection method: TLC
Appearance: Brown yellow powder
Main ingredients: Schizonepeta saponins, Schizonepeta flavonoids, etc
Mesh size: General extract powder 80-100
Product packaging: 1kg/aluminum foil bag; 25kg/cardboard drum
Storage: Avoid direct sunlight, cool, low temperature and dry environment
Shelf life: The shelf life is 24 months
Pharmaceutical-Grade Schizonepeta Saponin Extract
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a premier global B2B manufacturer of highly purified Schizonepeta Tenuifolia Extract (Japanese Catnip). We strictly source the aerial parts of Schizonepeta tenuifolia from controlled ecological bases, ensuring the raw material is exceptionally rich in natural bioactives and completely free from heavy metal and pesticide contamination.
Utilizing advanced macroporous resin chromatography and targeted impurity removal protocols, we successfully isolate and concentrate the plant's core therapeutic fraction: Schizonepeta Saponins. Standardized to an industry-leading purity of ≥98% via HPLC, our fine extract demonstrates profound efficacy in modulating immune responses, neutralizing oxidative stress, and exerting broad-spectrum anti-inflammatory action. It serves as a foundational Active Pharmaceutical Ingredient (API) for clinical antipyretics, high-end sensitive skincare formulations, and natural antimicrobial veterinary feed additives.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Aerial parts of Schizonepeta tenuifolia | Verified | Macroscopic ID |
| Total Saponins | ≥ 98.0% | 98.6% | HPLC |
| Appearance | Brown-yellow to fine powder | Complies | Visual Assessment |
| Solubility | Soluble in Hydro-ethanolic solutions | Complies | Solvent Test |
| Loss on Drying | ≤ 5.0% | 3.2% | USP <731> |
| Residue on Ignition | ≤ 3.0% | 1.5% | USP <281> |
| Heavy Metals (Pb, As) | ≤ 2.0 ppm / ≤ 1.0 ppm | < 0.5 ppm / < 0.1 ppm | ICP-MS |
| Pesticide Residues | Complies with EP/USP limits | Not Detected | GC-MS |
Manufacturing & Processing Excellence
Targeted Saponin Enrichment
Standard solvent extractions often fail to eliminate inert plant waxes and chlorophyll. Tihealth utilizes advanced macroporous resin column chromatography. This targeted purification protocol effectively strips away heavy impurities, allowing us to reliably scale production of ultra-pure ≥98% Schizonepeta Saponins.
Low-Thermal Processing
Schizonepeta bioactives are sensitive to thermal degradation. We implement a strict low-temperature vacuum evaporation system during solvent recovery. This ensures the complex molecular structures of the saponins remain entirely intact, maximizing their therapeutic and anti-inflammatory potency.
Global Compliance Standards
Operating under stringent cGMP and ISO 22716 (Cosmetics GMP) frameworks, our facility guarantees that every batch is pharmaceutical-grade. We strictly control microbiology and residual solvents, ensuring absolute safety for both internal medicine and topical dermatological applications.
Evidence-Based Pharmacological Mechanisms
Broad-Spectrum Anti-Inflammatory Action
Schizonepeta Saponins actively suppress the expression of pro-inflammatory cytokines and regulate localized inflammatory cascades. This provides profound, non-steroidal relief for sore throats, upper respiratory tract irritation, and chronic dermal erythema.
Immunomodulation & Antiviral Properties
Functions as a biological response modifier. It actively enhances the body's innate immune defenses, demonstrating significant clinical utility in combating early-stage viral infections (such as the common cold) and accelerating recovery from fever.
Dermatological Soothing & Repair
In topical applications, the high-purity saponins rapidly neutralize oxidative stress and tighten pores. It is exceptionally well-tolerated by sensitive skin, effectively reducing acne inflammation, localized pain, and allergic reactions without chemical irritation.
Gastrointestinal Microbiome Balancing
In veterinary and functional nutrition contexts, the extract acts as a powerful natural antimicrobial agent. It helps maintain the equilibrium of the intestinal microbiota, offering a sustainable, plant-based alternative to prophylactic antibiotics in animal feed.
Industrial Formulation Applications
Pharmaceutical R&D
The core Active Pharmaceutical Ingredient (API) for formulating natural antipyretic (fever-reducing) capsules, sore throat lozenges, and targeted anti-viral medications.
Premium Cosmeceuticals
Due to its high safety profile and potent anti-inflammatory properties, it is extensively used in high-end acne-clearing serums, sensitive-skin repair creams, and pore-minimizing toners.
Food Additives & Preservatives
Functions as a natural, plant-based antimicrobial additive, utilized by the food industry to safely extend product shelf life and prevent pathogenic contamination.
Veterinary & Animal Nutrition
Formulated into premium animal feed as a gut-health modulator and immune booster, serving as an effective, sustainable replacement for chemical antibiotics.
Contract Manufacturing & Global Supply Chain
♦ Custom Formulation Solutions
Beyond supplying pure ≥98% Saponin powder, Tihealth offers comprehensive contract manufacturing. Whether you require precise blending for cosmetic emulsions or customized liquid extracts, our engineering team executes to your exact blueprint.
♦ Traceable Quality Control
Quality is mathematically verifiable. Every batch undergoes strict cGMP-certified analysis. We provide full COAs, ensuring heavy metals, pathogens, and pesticide residues strictly comply with global pharmacopeial standards.
♦ Strict Brand Confidentiality
Secure IP protection via NDAs. We offer blind shipping, private label bulk packaging (from 1kg foil bags to 25kg sterile drums), and full FDA/EU regulatory documentation support for global customs clearance.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, oxidation-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. How do you guarantee the ≥98% Saponin purity?
We do not rely on crude gravimetric ratios. We utilize High-Performance Liquid Chromatography (HPLC) paired with certified reference standards to precisely quantify the Schizonepeta Saponin percentage, providing verifiable proof of potency on every COA.
02. Is this extract suitable for clear cosmetic serums?
Yes. Through our advanced macroporous resin purification, we remove heavy plant waxes and insoluble fibers. The resulting micro-powder dissolves seamlessly in hydro-ethanolic solutions and common cosmetic glycols, making it perfect for clear formulations without causing turbidity.
03. Does the extraction process destroy the plant's volatile oils?
While our primary target is the highly stable saponin fraction, we employ low-temperature vacuum evaporation to ensure that any synergistic volatile compounds are protected from thermal degradation, maintaining the extract's full therapeutic profile.
04. Does the product comply with cosmetic heavy metal limits?
Absolutely. Operating under cGMP and ISO 22716 guidelines, every batch is verified via ICP-MS. We guarantee extremely stringent heavy metal limits (e.g., Lead ≤ 2.0 ppm), ensuring total compliance for both pharmaceutical and premium skincare applications.
05. What is the Minimum Order Quantity (MOQ) and lead time?
Our standard MOQ for mass production is 25kg, packed in heavy-duty cardboard drums lined with double sterile, nitrogen-flushed bags. We also supply 1kg foil bags for pilot manufacturing and clinical R&D trials. Standard dispatch is within 7-10 days.
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