Echinacea Extract
CAS number: 70831-56-0
Product specifications: Purple Daisy Polyphenols 1% -4% Chicory Acid 1% -10%
For details, please consult customer service and customize according to customer needs
Extraction source: Dried Purple Daisy
Appearance description: Brown yellow powder
Detection method: HPLC
Product particle size: 99% pass through 80-100 mesh
Product application: Food raw materials
Storage method; Ventilated and dry, cool and insect proof, stored away from light
Packaging specifications: 1-5kg/aluminum foil bag, cardboard box, 25kg/cardboard drum
Shelf life: 24 months
Pharmaceutical-Grade Echinacea Extract (Cichoric Acid)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a specialized global B2B manufacturer of highly purified Echinacea Extract. We strictly source our raw botanical materials from the premium dried aerial parts and roots of Echinacea purpurea. Utilizing advanced dynamic hydro-ethanolic extraction combined with precision macroporous resin purification, we successfully isolate and protect the plant's core therapeutic caffeic acid derivatives: specifically Cichoric Acid and complex Polyphenols.
Rigorously standardized to deliver a customizable yield of 1% to 10% Cichoric Acid and 1% to 4% Total Polyphenols via HPLC, this brownish-yellow fine powder is globally recognized as a profound biological response modifier. By effectively stimulating macrophage phagocytosis and modulating inflammatory cytokine pathways, it serves as an indispensable Active Pharmaceutical Ingredient (API) for advanced immune-support supplements, upper respiratory tract infection (URTI) adjuvant therapies, and premium functional nutraceuticals.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Dried herb of Echinacea purpurea | Verified | Macroscopic ID |
| Cichoric Acid (Assay) | ≥ 1.0%, 2.0%, 4.0%, 10.0% | Conforms to Spec | HPLC |
| Total Polyphenols | ≥ 1.0% - 4.0% | 4.2% | UV Spectrophotometry |
| CAS Registry Number | 70831-56-0 (Cichoric Acid) | Matches Profile | Spectral Analysis |
| Appearance | Brownish-yellow fine powder | Complies | Visual Assessment |
| Particle Size | 99% passes through 80-100 mesh | Complies | USP <786> |
| Loss on Drying | ≤ 5.0% | 3.8% | USP <731> |
| Heavy Metals (Pb, As) | ≤ 10.0 ppm / ≤ 2.0 ppm | < 5.0 ppm / < 0.5 ppm | ICP-MS |
| Microbiology (Total Plate) | ≤ 1000 CFU/g | 160 CFU/g | ISO 4833-1 |
Manufacturing & Processing Excellence
Targeted Caffeic Acid Derivation
Cichoric acid is highly sensitive to oxidation and enzymatic degradation during extraction. Tihealth utilizes a controlled, low-temperature hydro-ethanolic solvent system that instantly deactivates endogenous plant enzymes, ensuring the absolute preservation of Cichoric Acid and Echinacosides without molecular fracturing.
Macroporous Resin Chromatography
To achieve high-purity specifications (up to 10% Cichoric Acid), we subject the crude extract to advanced macroporous adsorption resin chromatography. This rigorous molecular sieving strips away inactive structural starches and heavy plant waxes, resulting in a highly concentrated, bioavailable powder with excellent formulation characteristics.
Stringent Traceability & Safety
Operating under stringent GMP and ISO protocols, every batch of our Echinacea extract is verified via HPLC. The powder is instantaneously spray-dried and UV-sterilized, strictly ensuring that microbiology and heavy metal thresholds comply with US FDA and European Pharmacopoeia standards.
Evidence-Based Pharmacological Mechanisms
Profound Immunomodulation (Macrophage Activation)
Cichoric acid and complex polysaccharides synergistically function as highly potent biological response modifiers. They directly stimulate the phagocytic activity of macrophages and enhance the proliferation of T-lymphocytes and Natural Killer (NK) cells, fundamentally fortifying the body's innate cellular immunity.
Anti-Viral & URTI Defense
Extensively documented in global pharmacopeias, Echinacea extract interferes with viral cellular attachment and replication pathways. It is heavily utilized as an adjuvant to reduce the duration and severity of Upper Respiratory Tract Infections (URTIs), including the common cold and seasonal influenza.
Cellular Anti-Inflammatory Properties
Exhibits significant anti-inflammatory effects by inhibiting the cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic pathways. By suppressing the release of pro-inflammatory cytokines, it effectively mitigates systemic inflammation and localized tissue swelling.
Robust Antioxidant Defense
The dense polyphenol and caffeic acid matrix acts as a formidable scavenger of reactive oxygen species (ROS). It aggressively neutralizes free radicals, protecting cellular DNA and lipid membranes from environmental oxidative stress and delaying premature cellular senescence.
Industrial Formulation Applications
Immune-Support Nutraceuticals
The foundational API for premium dietary capsules, wellness gummies, and seasonal-defense tablets designed to fortify systemic immunity and white blood cell activity.
Pharmaceutical Adjuvants
Extensively utilized in the formulation of clinical botanical syrups, lozenges, and throat sprays focused on alleviating the symptoms of URTI and bronchial inflammation.
Functional Foods & Beverages
Integrated into health-focused RTD (Ready-to-Drink) botanical teas, immune-boosting energy shots, and enriched nutritional shakes.
Veterinary & Animal Nutrition
Employed as a high-end, natural feed additive to strengthen the innate immune resilience of livestock and companion animals, reducing reliance on synthetic antibiotics.
Contract Manufacturing & Global Supply Chain
♦ Precise Active Customization
We strictly tailor the concentration of Cichoric Acid (from 1.0% up to highly concentrated 10.0% specs) to perfectly match your specific formulation requirements and therapeutic claims.
♦ Traceable Quality Control
Quality is mathematically verifiable. Every batch undergoes strict cGMP-certified analysis via HPLC and UV. We provide full COAs, ensuring heavy metals, pathogens, and pesticide residues strictly comply with USP/EP standards.
♦ Secure Export Bulk Fulfillment
We specialize in botanical logistics. We offer blind shipping, bulk packaging (from 1kg sealed foil bags to 25kg sterile commercial drums), and full FDA/EU regulatory documentation support for rapid global customs clearance.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, moisture-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. What is the difference between Cichoric Acid and total Polyphenols?
"Polysphenols" is a broader classification encompassing various antioxidant compounds within Echinacea. Cichoric Acid is a highly specific, potent caffeic acid derivative that serves as the primary immunomodulatory biomarker. Tihealth's extraction process specifically targets and guarantees high concentrations of Cichoric Acid for precise therapeutic efficacy.
02. Is the extract completely water-soluble for beverage applications?
Yes. Through advanced macroporous resin purification and high-speed centrifugation, we strip away heavy insoluble plant waxes and fibers. The resulting micro-powder disperses rapidly in warm water, making it highly suitable for functional syrups and RTD wellness drinks without causing severe sedimentation.
03. How is the Cichoric Acid content validated?
We do not rely on basic UV methods which can yield false positives. We utilize High-Performance Liquid Chromatography (HPLC) to precisely isolate and quantify the exact percentage of Cichoric Acid, providing verifiable, pharmacopeia-aligned proof of potency on every COA.
04. Can you guarantee the product is free from heavy metals and pathogens?
Absolutely. We proactively mitigate contamination risks by sourcing exclusively from unpolluted, ecologically certified botanical zones. Every batch is verified via ICP-MS and rigorous microbiological plating to ensure parameters remain strictly below FDA and EU limits.
05. What is the Minimum Order Quantity (MOQ) and lead time?
Our standard MOQ for mass commercial production is 25kg, securely packed in heavy-duty cardboard drums lined with double sterile, moisture-proof bags. We also supply 1kg foil bags for pilot manufacturing and stability trials. Standard global dispatch is within 7-10 days.
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