Chicken Leg Mushroom Extract
Extraction source: Chicken leg mushroom
Specification content: 30:1；50:1；10:1&10%—50%
Detection method: TLC/UV
Product Appearance: Brown yellow powder
Packaging specifications: 1kg aluminum foil bag;
25kg cardboard drum
Storage method: It should be stored in a cool, ventilated, and dry place, avoiding direct sunlight
Shelf life: 24 months
Clinical-Grade Coprinus comatus Extract (Shaggy Ink Cap)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Operating at the forefront of mycological bio-engineering, Xi'an Tihealth supplies therapeutic-grade Coprinus comatus Extract (commonly referred to as the Chicken Leg Mushroom or Shaggy Mane). This specific fungal species is scientifically celebrated for its unique hypoglycemic properties. Because the mature fruiting bodies undergo rapid natural deliquescence (auto-digesting into black ink), we implement strict time-controlled harvesting and immediate flash-processing to capture its delicate active matrix.
Moving far beyond generic polysaccharide powders, our specialized acoustic cavitation protocols isolate the mushroom's exclusive bio-markers: The alkaloid 'Comatin' alongside trace organic Vanadium complexes. Standardized to a rigorous purity profile (≥30% macromolecular polysaccharides), our highly dispersible formulation exhibits insulin-mimetic behavior and robust pancreatic protection. It serves as a superior, natural Active Ingredient for metabolic health nutraceuticals, advanced blood-sugar management formulas, and clinical adjuvant nutrition.
Specification Profile & Quality Attributes
| Assay Parameter | Standard Limits | Lot Analysis (Typical) | Analytical Method |
|---|---|---|---|
| Morphological Origin | Cap and Stipe of C. comatus | Confirmed | Microscopy / HPTLC |
| Macromolecular Polysaccharides | ≥ 30.0% | 36.2% | Colorimetric Assay |
| Comatin (Alkaloid Fraction) | Positive / ≥ 1.0% | 1.4% | LC-MS |
| Organic Vanadium Trace | Present (Naturally occurring) | Complies | Atomic Absorption |
| Aqueous Dispersion | Readily soluble in warm water | Complies | Solvent Assessment |
| Moisture Content | ≤ 8.0% | 4.5% | Halogen Moisture Analyzer |
| Toxic Elements (Pb, Cd) | ≤ 1.0 ppm / ≤ 0.5 ppm | < 0.5 ppm / < 0.1 ppm | ICP-OES |
| Microbiological Limits | ≤ 1000 CFU/g (Total Plate) | < 100 CFU/g | AOAC Standards |
Industrial Processing Highlights
Anti-Deliquescence Flash Processing
Shaggy manes undergo rapid autolysis (enzymatically digesting into black ink) within hours of maturity. We bypass this catastrophic degradation by implementing immediate liquid-nitrogen flash-freezing directly at the cultivation source, entirely halting enzymatic breakdown and preserving the delicate alkaloid profile.
Cold-Process Acoustic Cavitation
To release the therapeutic vanadium complexes and Comatin without thermal damage, we replace aggressive boiling with targeted acoustic wave cavitation. This mechanically fractures the rigid fungal chitin matrices in a cold-water environment, achieving maximum active yields.
Selective Molecular Sieving
Post-extraction, the liquid undergoes a sophisticated molecular sieving cascade. This highly specific filtration removes inert structural glycoproteins and insoluble spores, resulting in an ultra-fine (D90≤50μm) powder that guarantees complete dispersion in commercial beverage matrices.
Targeted Therapeutic Mechanisms
Pancreatic β-Cell Protection (Hypoglycemic)
C. comatus is pharmacologically distinguished by its anti-diabetic potential. The unique alkaloid 'Comatin' paired with endogenous trace Vanadium exhibits insulin-mimetic properties. It actively protects pancreatic β-cells from functional exhaustion and assists in enhancing peripheral tissue glucose uptake.
Gastrointestinal Microbiome Harmony
The isolated arabinoxylans and specialized fungal polysaccharides act as resilient prebiotics. By resisting early enzymatic digestion, they successfully reach the colon to selectively ferment and nourish beneficial microbial communities, optimizing gut barrier integrity.
Hepatocyte Defense (Liver Function)
Demonstrates powerful protective effects against chemically induced hepatotoxicity. The bioactive matrix aids in regulating hepatic lipid metabolism, lowering elevated serum transaminases, and preventing abnormal fat deposition within liver tissues.
Innate Immune Modulation
The high-density complex carbohydrates bind effectively to Dectin-1 receptors on immune cells. This triggers a measured, non-inflammatory immune cascade, fortifying the body's natural resistance mechanisms during periods of physical fatigue or seasonal vulnerability.
Core Formulation Sectors
Glycemic Control Nutraceuticals
The premier botanical component for formulating targeted blood-sugar management capsules, insulin-sensitivity tablets, and diabetic-friendly metabolic complexes.
Clinical Adjuvant Nutrition
Integrated into specialized medical foods designed to support immunological resilience and hepatocyte recovery in physically compromised patients.
Clear Functional Beverages
Due to the stringent molecular sieving process, it disperses rapidly in liquid matrices, making it ideal for formulating metabolic functional shots and gut-health elixirs.
Geriatric Wellness Formulations
A highly valued additive for holistic longevity powders, leveraging its innate combination of immune-boosting polysaccharides and easily digestible fungal proteins.
White-Label Manufacturing & Procurement Logistics
♦ Custom Excipient Blending
We do not just supply raw powder. Our engineering team can adjust the polysaccharide ratios or create bespoke pre-mixes with other metabolic modulators (like Berberine) tailored specifically to your R&D blueprint.
♦ Stringent Analytical Auditing
All production lots are subjected to rigorous independent testing methodologies. We issue comprehensive Certificates of Analysis confirming exact active potencies and the strict limitation of heavy metals.
♦ Secure Commercial Fulfillment
Protecting your intellectual property is paramount. We operate under stringent confidentiality agreements, providing seamless bulk manufacturing, custom private-label packaging, and comprehensive export documentation.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, oxidation-free cross-border transit for our B2B procurement partners.
Procurement & Formulation FAQ
01. What makes Coprinus comatus different from other mushrooms for metabolic health?
Unlike standard functional fungi, C. comatus uniquely possesses 'Comatin'-a specific alkaloid-and naturally accumulates trace organic Vanadium. This combination is heavily cited in clinical literature for its distinct insulin-mimetic (hypoglycemic) properties, making it superior for blood-sugar management formulations.
02. How do you prevent the natural "inking" (autolysis) of the mushroom?
This is our core technical barrier. The mushroom physically digests itself within hours of harvest. We deploy immediate liquid-nitrogen flash-freezing directly at our cultivation sites, instantly arresting the autolytic enzymes and preserving the delicate phytochemical matrix for subsequent extraction.
03. Is this extract fully soluble for liquid formulations?
Yes. By utilizing precision molecular sieving, we strip away the heavy, insoluble structural chitins and spores. The resulting fine powder disperses seamlessly in aqueous environments, making it ideal for RTD functional beverages without unwanted sedimentation.
04. Does the extract contain dangerous levels of Vanadium?
No. The Vanadium present is in trace, naturally occurring organic complexes, which are highly bioavailable and entirely safe for daily dietary supplementation. Furthermore, all batches are rigorously tested via ICP-OES to ensure toxic heavy metals (Pb, Cd) remain far below regulatory thresholds.
05. What are your commercial supply constraints and packing parameters?
Our industrial baseline requirement is 25 kilograms per dispatch, securely packaged in rigid commercial drums with sterile double-liners. We maintain a robust inventory for immediate global dispatch, while bespoke extractions or custom blends require standard production lead times.
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