Cordyceps Extract
English name: Cordycepin
CAS NO: 73-03-0
Product alias: Cordycepin, Cordycepin, Cordycepin
Main ingredient: Cordycepin
Specifications: Cordycepin 98%&1%,
Cordyceps mycelium powder,
Cordyceps sinensis extract 10:1,
Cordyceps polysaccharides 5% -60%
Appearance: Fine white powder
Characteristic: soluble in water
Source: Cordyceps militaris
Detection method: HPLC
Storage method: Store in a cool and dry place, away from light and high temperatures.
Shelf life: 24 months
Standardized Cordyceps Militaris Extract (Cordycepin API)
Technical Data Sheet (TDS) & Analytical Control
| Analytical Parameter | Target Specification Limit | Result (Typical Batch) | Validated Methodology |
|---|---|---|---|
| Botanical Source | Cultivated Cordyceps militaris (Fruiting Body) | Verified | Macroscopic ID |
| Cordycepin (CAS: 73-03-0) | ≥ 1.0% / 3.0% / 5.0% (Customizable) | 1.15% / 3.2% | HPLC-UV (260nm) |
| Total Polysaccharides | ≥ 30.0% | 32.8% | UV Spectrophotometry |
| Appearance | Brown-yellow to deep yellow fine powder | Complies | Visual Assessment |
| Aqueous Solubility | Fully dispersible / soluble in water at 25°C | Complies | Gravimetric Dispersion |
| Loss on Drying | ≤ 5.0% | 3.4% | USP <731> |
| Heavy Metals (Pb, As, Cd) | Pb ≤ 2.0 ppm, As ≤ 1.0 ppm | Complies | ICP-MS (USP <233>) |
| Microbiology (Total Plate) | ≤ 1000 CFU/g | Pathogens: Negative | < 50 CFU/g | USP <2021> / <2022> |
Extraction & Cultivation Excellence
Vegan Solid-State Fermentation
Wild cordyceps grows on insect larvae, which poses allergen and ethical sourcing issues. We utilize an advanced solid-state fermentation protocol growing C. militaris on a 100% plant-based (wheat/rice) sterile substrate. This ensures an entirely Vegan, heavy-metal-free biomass while drastically scaling Cordycepin accumulation.
Enzymatic Degradation Control
Cordycepin is notoriously unstable; heat and endogenous enzymes (like ADA) rapidly degrade it during traditional water boiling. Tihealth deploys a rapid, low-temperature vacuum extraction sequence that denatures the destructive enzymes immediately, preserving the structural integrity of the 3'-deoxyadenosine molecule.
Resin Purification (Clear Dispersion)
Standard mushroom powders leave heavy, gritty sediment in liquid formulations. By utilizing macroporous resin chromatography and sub-micron ultrafiltration, we strip out insoluble chitins and heavy starches, resulting in a highly concentrated extract that dissolves beautifully into functional RTD beverages.
ATP Biosynthesis & Pharmacological Action
Cellular ATP Upregulation & VO2 Max
Cordycepin is a direct structural analogue of adenosine. It integrates seamlessly into cellular metabolic pathways, optimizing oxygen utilization (increasing VO2 Max) and accelerating the biosynthesis of Adenosine Triphosphate (ATP) in skeletal muscle and cardiac tissue. This provides a clean, non-jittery energy source superior to caffeine.
AMPK Pathway Activation (Fatigue Delay)
Acts as a potent biological activator of AMP-activated protein kinase (AMPK). This critical enzymatic switch shifts cellular metabolism towards efficient lipid oxidation and sustained energy production, effectively delaying physical exhaustion and dramatically improving post-workout recovery rates.
Immunomodulatory & Respiratory Synergy
The high-density beta-glucans (≥30% polysaccharides) within the extract work synergistically with Cordycepin to stimulate macrophage and Natural Killer (NK) cell activity. Furthermore, it relaxes bronchial smooth muscles, enhancing airway dilation and supporting robust respiratory function during high-stress activities.
Industrial Formulation Applications
Sports Nutrition & Pre-Workouts
The premier stimulant-free ATP booster for elite athletic formulations, pre-workout powders, and endurance gels designed to increase VO2 Max without the caffeine crash.
Men's Vitality Supplements
A core adaptogenic API utilized in men's health capsules and testosterone-support blends to combat chronic fatigue, improve microcirculation, and support stamina.
Immune & Respiratory Defense
Formulated into clinical-grade dietary capsules specifically targeting respiratory tract protection and systemic immune response modulation.
Functional RTD Beverages
Because of its excellent water solubility (due to ultrafiltration), it blends perfectly into ready-to-drink energy elixirs and "medicinal mushroom" coffees.
Packaging, Logistics & Secure Payment
We provide pharmaceutical-grade aseptic packaging, efficient global logistics with strict CITES/Botanical compliance support, and secure multi-currency payment methods to ensure seamless cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
Q1: Why do you use Cordyceps militaris instead of Cordyceps sinensis?
Wild Cordyceps sinensis is an endangered, hyper-expensive species with virtually undetectable levels of Cordycepin (the true active compound). By utilizing advanced solid-state cultivation of Cordyceps militaris fruiting bodies, Xi'an Tihealth sustainably produces an extract with up to 90 times higher Cordycepin concentration, delivering superior, reproducible clinical efficacy for industrial formulation while bypassing ethical sourcing issues.
Q2: How do you verify the authenticity of the Polysaccharide content?
The botanical extract market is often plagued by adulteration (spiking with cheap maltodextrin to inflate UV polysaccharide readings). We utilize rigorous iodine-potassium iodide testing and molecular weight distribution (SEC-HPLC) to guarantee that our ≥ 30% polysaccharide content is entirely derived from genuine fungal beta-glucans, not exogenous starches.
Q3: Fungi are hyper-accumulators. Is this extract safe from Heavy Metals?
Yes. Because we use indoor, controlled solid-state cultivation on sterile plant-based substrates (wheat/rice), the growing environment is entirely isolated from polluted soil. Every batch is validated via ICP-MS to ensure Lead (Pb) ≤ 2.0 ppm and Arsenic (As) ≤ 1.0 ppm, strictly complying with FDA and EFSA dietary supplement limits.
Q4: Will this powder dissolve clearly in sports or energy drinks?
Absolutely. Our downstream processing includes macroporous resin purification and sub-micron cross-flow filtration. This completely strips away the insoluble chitin (fungal cell walls), resulting in a fine powder that disperses and dissolves clearly in aqueous solutions without leaving gritty sediment.
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