Bacopa Monnieri Extract
Latin name: Bacopa monnieri (L.)
Product source: Natural plant extract
Content specification: ≥ 50% Bacosides
CAS number: 93164-89-7
Testing method: HPLC
Active ingredient: Bacosides A & B
Product packaging: 1kg/bag; 25kg/drum
Product storage: Sealed, cool, dry and dark place
Shelf life: 24 months
Standardized Bacopa Monnieri Extract (Bacosides API)
Technical Data Sheet (TDS) & Analytical Control
| Analytical Parameter | Target Specification Limit | Result (Typical Batch) | Validated Methodology |
|---|---|---|---|
| Taxonomic Botanical Source | Aerial parts of Bacopa monnieri (L.) Wettst. | Verified | Macroscopic ID / TLC |
| Total Bacosides Assay | ≥ 20.0% / ≥ 50.0% | 21.5% / 52.4% | UV Spectrophotometry |
| Bacoside A & B (Optional) | Customizable Pharmaceutical Grade | Conforms | HPLC |
| Appearance & Taste | Brown to yellowish-brown powder, bitter taste | Complies | Visual / Organoleptic |
| Loss on Drying | ≤ 5.0% | 3.8% | USP <731> |
| Heavy Metals (Pb, As, Cd) | Pb ≤ 2.0 ppm, As ≤ 1.0 ppm | Complies | ICP-MS (USP <233>) |
| Microbiological Limits | Total Plate ≤ 10,000 CFU/g | Pathogens: ND | < 500 CFU/g | USP <2021> / <2022> |
Manufacturing & Sourcing Excellence
Marshland Contaminant Auditing
Because Bacopa Monnieri is an aquatic/marsh plant, wild-harvested material consistently fails EU and FDA heavy metal audits (especially for Lead and Arsenic). We eliminate this risk entirely. By sourcing only from controlled, GAP-certified fresh-water basins, we ensure an ultra-pure biomass foundation before extraction even begins.
Macroporous Resin Purification
Crude Bacopa extracts are laden with inert plant starches that dilute potency and create formulation instability. We utilize advanced macroporous resin column chromatography. This targeted molecular sieving captures the active Bacoside saponins and purges the impurities, allowing us to achieve stable concentrations up to 50%.
Dual Analytical Validation
We cater to diverse regulatory markets. We offer standard UV Spectrophotometry analysis (measuring total saponins) for cost-effective supplement lines, as well as high-resolution HPLC analysis to precisely quantify Bacoside A and B for premium, clinical-grade neurological brands.
Evidence-Based Nootropic Mechanisms
Synaptic Communication & Memory Consolidation
Bacosides are clinically observed to enhance kinase activity and neuronal synthesis. This biochemical action promotes the proliferation of dendrites (dendritic arborization) in the brain, significantly improving the speed and efficiency of synaptic communication crucial for learning and memory retention.
Acetylcholine Regulation (Focus & Attention)
Bacopa Monnieri acts as a natural acetylcholinesterase inhibitor. By slowing the enzymatic breakdown of acetylcholine-a vital neurotransmitter for cognitive focus and alertness-it supports sustained mental energy and mitigates the symptoms of attention-deficit conditions.
Targeted Neuro-Antioxidant Defense
Unlike systemic antioxidants, Bacosides cross the blood-brain barrier effectively. They neutralize free radicals (such as superoxide and hydroxyl radicals) specifically within the prefrontal cortex and hippocampus, protecting neural tissues from oxidative stress and age-related cognitive decline.
Industrial Formulation Applications
Nootropic & Cognitive Stacks
The core Active Pharmaceutical Ingredient (API) for formulating premium brain-boosting capsules, often synergized with Ginkgo Biloba, L-Theanine, or Lion's Mane.
Adaptogenic Stress-Relief Formulas
Heavily utilized in supplements targeting cortisol regulation and general anxiety, offering a calming effect without the sedative drowsiness of traditional sleep aids.
Healthy Aging & Neuro-protection
Sourced by clinical brands designing dietary complexes focused on delaying age-related memory loss and maintaining neuro-plasticity in geriatric demographics.
Functional Gummies & Beverages
With proper flavor-masking (due to its natural bitterness), it is integrated into high-value cognitive energy shots and focus-enhancing gummy vitamins.
Packaging, Logistics & Secure Payment
We provide pharmaceutical-grade aseptic packaging, efficient global logistics with dual customs clearance support, and secure multi-currency payment methods to ensure seamless cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
Q1: Why do some Bacopa extracts fail heavy metal testing in the EU/US markets?
Bacopa is a wetland/aquatic plant that aggressively bio-accumulates environmental toxins. Wild-harvested material from polluted waterways frequently fails heavy metal limits. Xi'an Tihealth entirely mitigates this risk by cultivating our biomass in unpolluted, controlled fresh-water environments. Every batch is verified via ICP-MS to ensure strict compliance (Pb ≤ 2.0 ppm, As ≤ 1.0 ppm).
Q2: What is the difference between testing Bacosides via UV vs. HPLC?
UV Spectrophotometry measures "Total Saponins," which is an industry standard and highly cost-effective for general formulations. However, HPLC testing specifically targets and isolates the individual active molecules (Bacoside A and Bacoside B). We offer both standardization metrics to align with your specific budgetary needs and label claims.
Q3: Is the extract extremely bitter? Can it be used in gummies?
Yes, natural bacosides are intensely bitter and astringent. While perfect for swallowed capsules and tablets, formulating it into gummies or liquids requires expertise. If you are developing a flavored product, we recommend working with your flavor house for masking agents, or consulting our R&D team regarding micro-encapsulated (de-bittered) variations.
Q4: Is the powder water-soluble?
Standard Bacopa extracts are only partially soluble in water because the high-concentration saponins are lipophilic (fat-loving). While it disperses reasonably well, it will not form a perfectly clear solution. It is ideal for cloudy functional drinks, but not recommended for transparent water formulations without emulsification.
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