Rhodiola Rosea Extract
Lattin name: Rhodiola sacra (Prain ex Hamet) Fu
CAS NO: 10338-51-9
Product color: Brown Red powder to white powder
Product Specifications: 1%-98%HPLC
Plant source: This product is extracted from the rhizome of Rhodiola rosea in the Sedaceae family.
Storage time: 24 months
Product packaging: 1kg / bag 25kg / drum
Pharmaceutical-Grade Rhodiola Rosea Extract (Adaptogen API)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a premier global B2B manufacturer of authentic, highly standardized Rhodiola Rosea Extract. Distinguishing ourselves from suppliers utilizing inferior Rhodiola crenulata (which severely lacks the critical Rosavins compound), we rigorously source exclusively from genuine, wild-harvested Rhodiola rosea L. roots found in extreme, high-altitude alpine environments. This harsh climate naturally triggers a profound accumulation of secondary metabolites, ensuring maximum phytochemical potency.
Utilizing advanced microwave-assisted aqueous extraction coupled with precision macroporous resin chromatography, we expertly isolate the plant's core therapeutic markers. Our extract is rigorously standardized to deliver the globally recognized "Golden Ratio"-≥ 3.0% Salidroside and ≥ 3.0% Rosavins (HPLC validated). Clinically revered as a premier botanical Adaptogen, this brownish-yellow fine powder effectively mitigates physical fatigue, shields against hypoxic stress, and significantly enhances cognitive (nootropic) function. Exhibiting excellent aqueous solubility and absolute microbiological safety, it serves as an indispensable Active Pharmaceutical Ingredient (API) for advanced sports nutrition, anti-stress nutraceuticals, and high-end cellular longevity formulations.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Dried roots of genuine Rhodiola rosea L. | Verified | Macroscopic ID / TLC |
| Salidroside Assay | ≥ 1.0%, 3.0%, 5.0%, 98% | Conforms to Spec | HPLC |
| Total Rosavins Assay | ≥ 3.0% - 5.0% | 3.25% | HPLC |
| CAS / Molecular Formula | 10338-51-9 (Salidroside) | Matches Profile | Spectral Analysis |
| Appearance | Brownish-yellow fine powder | Complies | Visual Assessment |
| Solubility | 100% Water Soluble (Clear solution) | Complies | Aqueous Dispersion |
| Loss on Drying | ≤ 5.0% | 3.4% | USP <731> |
| Heavy Metals (Pb, As) | ≤ 10.0 ppm / ≤ 2.0 ppm | < 5.0 ppm / < 0.5 ppm | ICP-MS |
| Microbiology (Total Plate) | ≤ 1000 CFU/g | < 100 CFU/g | ISO 4833-1 |
Manufacturing & Processing Excellence
Targeted Dual-Biomarker Extraction
Crude boiling severely degrades thermolabile glycosides. Tihealth utilizes advanced microwave-assisted, low-temperature aqueous extraction. This method effectively penetrates the dense cellular matrix of wild roots, maximizing the simultaneous yield and structural preservation of both the critical phenylpropanoids (Rosavins) and phenylethanol derivatives (Salidroside).
Macroporous Resin Chromatography
To achieve ultra-high pharmaceutical purities (up to 98% Salidroside) and clear aqueous solubility, the concentrated extract is subjected to specific AB-8 macroporous adsorption resin chromatography. This rigorous molecular sieving strips away heavy plant waxes, inert starches, and heavy metals, yielding a pristine, highly bioavailable powder.
Strict Botanical Authentication
The global market is heavily adulterated with cheaper Rhodiola crenulata. We implement strict TLC and DNA barcoding to definitively guarantee the exclusive use of R. rosea. This uncompromising authentication is the only way to deliver the Rosavins necessary for true, clinical-grade adaptogenic efficacy.
Evidence-Based Pharmacological Mechanisms
Adaptogenic Stress Response (HPA Axis Regulation)
Rhodiola Rosea is clinically classified as a premier botanical adaptogen. Salidroside and Rosavins actively regulate the Hypothalamic-Pituitary-Adrenal (HPA) axis. By modulating the release of cortisol and balancing critical stress-response neuropeptides, it profoundly enhances the body's resilience to acute physical, emotional, and environmental stressors.
Nootropic Cognitive Enhancement & Neuroprotection
Exhibits significant neuroprotective and cognitive-enhancing (nootropic) properties. It actively stimulates the synthesis of neurotransmitters (dopamine, serotonin) and protects neuronal cells from hypoxia (oxygen deprivation) and ischemic damage. This mechanism is critical for improving mental clarity, focus, and memory retention under extreme fatigue.
Cellular ATP Generation & Anti-Fatigue
Directly supports mitochondrial function and stimulates the synthesis of Adenosine Triphosphate (ATP) in muscle tissues. By significantly reducing the accumulation of Lactic Acid (LDH) and Creatine Kinase (CK) during intense exertion, it dramatically accelerates muscular recovery and extends physical endurance.
Robust Antioxidant & Cellular Longevity
Possessing an exceptionally high ORAC (Oxygen Radical Absorbance Capacity) value, the complex polyphenolic matrix aggressively scavenges reactive oxygen species (ROS). It mitigates cellular oxidative stress, protects cardiovascular endothelium, and delays premature cellular senescence, making it highly valuable in anti-aging applications.
Industrial Formulation Applications
Nootropic & Cognitive Supplements
The premier botanical API for formulating brain-boosting capsules, focus-enhancing gummies, and supplements targeting mental fatigue and neurodegenerative prevention.
Sports Nutrition & Endurance
A foundational ingredient in high-performance pre-workout powders and post-recovery formulations designed to accelerate ATP synthesis and clear lactic acid.
Functional RTD Beverages
Our highly purified, 100% water-soluble grades integrate seamlessly into clear functional energy elixirs, adaptogenic teas, and anti-stress botanical drinks.
Premium Anti-Aging Cosmeceuticals
Incorporated into high-end anti-aging serums and topical creams to leverage its profound antioxidant capacity, protecting dermal fibroblasts from UV photoaging.
Contract Manufacturing & Global Supply Chain
♦ Precise Active Customization
We empower B2B buyers with strict specification control. From the standard 3% Salidroside / 3% Rosavins adaptogenic baseline to ultra-pure 98% Salidroside for pharmaceutical R&D, our extraction is fully customizable.
♦ Traceable Quality Control
Quality is mathematically verifiable. Every batch undergoes strict cGMP-certified analysis via HPLC. We provide full COAs, ensuring heavy metals, pathogens, and pesticide residues strictly comply with USP and EP safety standards.
♦ Secure Export Bulk Fulfillment
We specialize in global botanical logistics. We offer blind shipping, bulk private label packaging (from 1kg foil bags to 25kg sterile drums), and full FDA/EU regulatory documentation support for rapid global customs clearance.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, moisture-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. Why choose Tihealth's Rhodiola Rosea over low-cost suppliers?
Authenticity is critical. Many low-cost powders utilize cheaper Rhodiola crenulata, which inherently lacks the crucial Rosavins, or they spike the powder with synthetic Salidroside. Tihealth rigorously authenticates our raw material to ensure 100% genuine, wild-harvested R. rosea L., providing true, full-spectrum clinical efficacy.
02. Is the extract completely water-soluble for beverage applications?
Yes. Through advanced macroporous resin ultrafiltration and high-speed centrifugation, we completely remove heavy insoluble plant waxes and cellular chitins. The resulting micro-powder disperses rapidly and clearly in cold water, making it perfect for functional RTD energy drinks without causing sedimentation.
03. Does your Rhodiola extract meet European (EP) or American (USP) standards?
Absolutely. Because wild alpine botanicals can bioaccumulate trace elements, we proactively mitigate this risk. Every batch is verified via ICP-MS to ensure that heavy metals (Pb <3ppm, As <2ppm) and pesticide residues remain strictly below FDA and EU pharmacopeial safety thresholds.
04. What is the lead time for bulk Rhodiola Rosea orders?
For our standard 3% Salidroside / 3% Rosavins specification, we maintain robust rolling inventory. Orders under 500kg are securely packed in 25kg sterile drums and are typically dispatched within 3-5 working days upon payment verification.
05. Do you supply Free Samples for R&D formulation testing?
Yes, we actively support B2B formulation development. We can provide 10g - 20g free samples along with batch-specific Certificates of Analysis (COA) for qualified manufacturers to perform HPLC assay testing and solubility trials.
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