Magnesium L-Threonate API CAS 778571-57-6
Synonyms: Magtein analogue, L-Threonic acid magnesium salt
CAS: 778571-57-6
Specification: ≥99%
Test Method: HPLC
Appearance: White fine powder, no crystals, no odor
Solubility: Good water solubility
Product packaging: 1kg/bag; 25kg/drum
Product storage: Sealed, cool, dry & dark place (15–25°C)
Shelf life: 24 months

Magnesium L-Threonate API Powder | CAS 778571-57-6 | Brain-Permeable Magnesium Chelate
Magnesium L-Threonate (CAS No. 778571-57-6) is a breakthrough mineral chelate specifically engineered to bypass the Blood-Brain Barrier (BBB). While standard magnesium salts exhibit low cerebral bioavailability, the L-threonate ligand acts as a high-affinity chaperone, directly elevating magnesium ion concentration in the brain tissue and cerebrospinal fluid (CSF). At Xi'an Tihealth, we provide a ≥99% purity API designed for advanced nootropic formulations, facilitating synaptic plasticity restoration and cognitive resilience. Our synthesis is patent-compliant, ensuring a zero-risk supply chain for global premium brands targeting neuro-regeneration and brain-fog mitigation.
⚠️ REGULATORY COMPLIANCE & MANUFACTURING NOTICE
Professional Use Specification: This ≥ 99% purity Magnesium L-Threonate is supplied as a raw material API powder for professional laboratory research and industrial nutriceutical manufacturing. It is NOT a finished consumer product.
Integrity Assurance: Xi'an Tihealth provides genuine structural Magnesium L-Threonate, verified for its specific molecular chelation. We assume no liability for unauthorized direct usage or legal consequences arising from the use of adulterated analogues in the retail market.
Biochemical Mechanism: Synaptic Density and Neuro-Regeneration
Magnesium L-Threonate facilitates neuro-cognitive homeostasis through targeted molecular pathways:
- Synaptic Arborization: By increasing the density of presynaptic release sites and supporting neurite outgrowth, it reverses the age-related decline in synaptic plasticity.
- NMDA Receptor Modulation: It maintains the magnesium blockade of the NMDA receptor, preventing calcium-induced excitotoxicity while ensuring efficient Long-Term Potentiation (LTP).
- Cognitive Buffer: Clinical R&D indicates a significant reduction in "brain fog" and mental fatigue by stabilizing mitochondrial energetic output in neuronal cells.
Technical Specifications and Ultra-Low Impurity Audit
| Parameter | Pharmaceutical Specification |
|---|---|
| Assay (HPLC, Dry Basis) | ≥ 99.0% (High Batch Consistency) |
| Lead (Pb) | ≤ 1.0 ppm |
| Arsenic (As) | ≤ 0.5 ppm |
| Cadmium (Cd) / Mercury (Hg) | ≤ 0.1 ppm |
| Microbial Control | TPC ≤ 1000 cfu/g (Full Food/Nutra Grade) |
Bench Note: Unlike imitation salts, Xi'an Tihealth's L-Threonate exhibits superior physical stability-no moisture absorption and no caking. This ensures high-speed compatibility with encapsulation and tableting equipment without downtime.
Global R&D and Procurement FAQ
Our production utilizes a patent-compliant synthetic pathway that bypasses protected methodologies. We provide full legal and technical dossiers to ensure your end-product remains safe from intellectual property litigation in the US and EU markets.
What defines "Genuine Structural Magnesium L-Threonate" at your facility?
Many imitations are simply physical mixtures of magnesium oxide and threonic acid. Our API is a true chelate, verified via NMR and IR spectroscopy to ensure the molecular structure is intact, providing the specific lipophilicity required for BBB penetration.
Can you provide private labeling and customized specifications?
Yes. Our GMP-like clean workshop supports large-scale supply and customized mesh sizes or bulk densities. We offer comprehensive OEM/ODM support for brands targeting nootropic shots, capsules, and anti-aging brain formulas.
Xi'an Tihealth Biotechnology Compliance Statement: Specialized mineral API for professional industrial R&D only. ISO 9001:2015 Certified. Non-GMO. Allergen-Free.
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