Semaglutide Intermediate P29 Powder, GLP-1 Cas No.1169630-82-3
Product source: Chemical Synthesis
Content specification: ≥ 95% (HPLC)
CAS NO:1169630-82-3
Detection methods: HPLC, LC-MS
Active ingredient: GLP-1 (9-37)
Product mesh: 100-200 mesh
Product Description: White or off white powder;Has hygroscopicity.
Product Usage: Used for the production of semaglutide
Product packaging: 1g, 5g, 10g, 25g, 50g, 100g, etc
Product storage: Store in a sealed, dark, and dry environment at -20 ° C or lower temperatures (such as -80 ° C).
Shelf life: 24 months
Semaglutide Intermediate P29 (GLP-1 9-37)
CAS: 1169630-82-3 | PHARMACEUTICAL-GRADE SYNTHETIC PEPTIDE
Strategic Backbone for Semaglutide Synthesis
The P29 intermediate (GLP-1 9-37) is the fundamental peptide sequence required for industrial Semaglutide manufacturing. Xi'an Tihealth utilizes high-precision Solid-Phase Peptide Synthesis (SPPS) to guarantee sequence fidelity. We rigorously manage the deletion sequence profile to ensure that your downstream Lys26 acylation and therapeutic conjugation reactions achieve maximum conversion yields.
Our production follows strict GMP-aligned controls, delivering a Non-Animal Origin (NAO) peptide that is fully traceable, minimizing regulatory friction during drug substance CMC filings.
Download Full COA & DossierTechnical Specifications
- ✓ Purity (HPLC): ≥95.0%
- ✓ Sequence: GLP-1(9-37)
- ✓ Synthesis: SPPS (Non-Animal)
- ✓ Appearance: White Hygroscopic Powder
- ✓ Stability: -20°C Stored
Optimized for Lys26 Acylation
Our P29 backbone provides the exact architectural accessibility required for the site-specific conjugation of the C18 fatty diacid side chain, a critical step in creating the Semaglutide therapeutic profile.
High-pH Solubility Profile
Engineered for high solubility in alkaline media (pH 11.0–11.5). This ensures a clean, monomeric reaction solution, preventing aggregation and increasing overall coupling efficiency.
Regulatory Ready
Provided with comprehensive technical dossier support, including impurity profiling (LC-MS) to meet global regulatory Chemistry, Manufacturing, and Controls (CMC) requirements.
Regulatory & Handling Transparency
We utilize high-resolution Mass Spectrometry (LC-MS) to verify molecular weight and Amino Acid Analysis (AAA) to confirm sequence composition. This ensures the 29-residue peptide matches the target sequence with no truncated byproducts.
Q: What is the mandatory storage condition for P29?P29 is extremely hygroscopic and temperature-sensitive. It must be stored at -20°C (or -80°C for long-term stability). It should be kept in a vacuum-sealed, moisture-proof environment. We provide cold-chain shipping with dry ice for all international orders.
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