Huperzine A API CAS 102518-79-6
Product source: Natural plant extract
Content specification: ≥99%
CAS number: 102518-79-6
Testing method: HPLC
Active ingredient: Huperzine A
Product packaging: 1kg/bag; 25kg/drum
Product storage: Sealed, cool, dry and dark place
Shelf life: 24 months
Huperzine A API (≥99%)
Selective Acetylcholinesterase (AChE) Inhibitor | CAS 102518-79-6
1. Product Description
Xi'an Tihealth supplies pharmaceutical-grade Huperzine A (CAS 102518-79-6) as a high-purity (≥99%) crystalline powder. This sesquiterpene alkaloid is extracted from Huperzia serrata and serves as a selective, reversible inhibitor of acetylcholinesterase (AChE). Our API is audited for strict enantiomeric purity (L-isomer dominance), ensuring stable biological activity for microgram-level dosing in professional R&D and pharmaceutical manufacturing environments.
2. Pharmacological Mechanism
- AChE Inhibition: Functions by reversibly binding to the catalytic active site of the acetylcholinesterase enzyme, thereby reducing the hydrolysis rate of acetylcholine within the synaptic cleft.
- Stereospecific Potency: Our production process prioritizes the L-isomer, which demonstrates documented superior binding affinity compared to synthetic racemic mixtures.
- Excitotoxicity Mitigation: Acts as a modulator for NMDA receptors, supporting the protection of neural pathways from glutamate-induced stress.
3. Technical Data Sheet (TDS)
| Parameter | Specification |
|---|---|
| Assay (HPLC) | ≥ 99.0% |
| Optical Rotation | -52.0° ~ -56.0° |
| Heavy Metals | ≤ 10 ppm |
| Microbial Control | ≤ 100 cfu/g |
⚠️ Handling Protocol & RUO Disclaimer
This product is a potent API powder intended strictly for Research Use Only (RUO) and industrial manufacturing. Given the microgram-level biological activity, handlers must utilize micro-analytical balances and high-efficiency particulate air (HEPA) containment systems. Xi'an Tihealth provides full batch documentation (BMR/MOA) for authorized audit purposes. Not for direct human consumption.
4. Technical FAQ
Why is HPLC quantification essential for Huperzine A?Due to the extremely low effective dosage range (µg), minor discrepancies in API purity can result in significant deviations in pharmacological outcome. Our HPLC-standardized process ensures a Coefficient of Variation (CV) ≤ 5%, providing the accuracy required for high-precision pharmaceutical formulating.
Does Tihealth support Regulatory Documentation for DMF?Yes. We supply comprehensive technical dossiers including validated test methods, stability testing protocols, and impurity profiles to assist our partners in local drug registration and site audits.
Hot Tags: huperzine a api cas 102518-79-6, China huperzine a api cas 102518-79-6 manufacturers, suppliers, factory, hialuronato de sodio hialuronato sodico sodium hyaluronate, , , sodium hyaluronate dan hyaluronic acid, sodium retinoyl hyaluronate
You Might Also Like
Send Inquiry