High-Purity Ectoine Powder (Extremolyte API) | CAS 96702-03-3

Ectoine (CAS No. 96702-03-3), a powerful natural extremolyte, is a cyclic amino acid derivative originally isolated from halophilic microorganisms surviving in extreme environments. As a premier bioactive ingredient supplier, Xi'an Tihealth manufactures pharmaceutical and premium cosmetic-grade Ectoine powder with an HPLC-validated purity of ≥99.0%. By functioning as an osmo-protectant at the cellular level, our Ectoine API provides unparalleled stability, potent proteostasis, and extreme environmental stress protection. It is strategically formulated into high-end dermo-cosmetics, medical device dressings, and specialized ophthalmic solutions.

Xi'an Tihealth guarantees exceptional batch-to-batch consistency. Our specialized fermentation and purification processes yield a product free from toxic impurities, suitable for both topical and mucosal applications.

Ectoine exerts its protective effects through a biophysical principle known as "Preferential Exclusion":

• Hydration Shell Formation: As a highly polar kosmotropic molecule, Ectoine exhibits an exceptional affinity for water. It orchestrates water molecules to form stable, dense hydration shells surrounding cellular structures, proteins, and cell membranes.
• Biomolecular Stabilization: Without interacting directly with proteins, the dense water layer thermodynamically stabilizes protein folding. This prevents enzyme denaturation and cellular apoptosis induced by UV radiation, heat, and chemical irritants.
• Osmotic Regulation & Barrier Repair: It acts as a compatible solute, maintaining intra- and extra-cellular osmotic balance, significantly reducing Transepidermal Water Loss (TEWL) and accelerating the repair of compromised lipid barriers.

• Medical Devices & Pharma: Formulated into ophthalmic solutions (eye drops) for dry eye syndrome and allergic conjunctivitis, as well as nasal sprays targeting allergic rhinitis, due to its mucosal-soothing and anti-inflammatory properties.
• Advanced Dermo-Cosmetics: The active of choice for anti-aging serums, photo-protection (sunscreen) formulations, and intensive barrier-repair creams for sensitive, eczema-prone, or post-procedure skin.
• Formulation Compatibility: Ectoine powder is highly water-soluble, non-ionic, and exceptionally stable across extreme pH ranges (1-9) and high processing temperatures, making it a formulator-friendly active ingredient.

While both grades offer high purity (≥99%), our pharmaceutical-grade Ectoine undergoes ultra-filtration to strictly control bacterial endotoxins and microbiological limits, ensuring compliance for sterile applications like ophthalmic solutions and injectable medical devices.

2,How soluble is Ectoine powder, and at what stage should it be added to formulations?

Ectoine is highly soluble in water (approx. 540 g/L at room temperature) but insoluble in lipophilic solvents. Due to its exceptional thermal stability, it can be added to the aqueous phase either before emulsification/heating or during the cool-down phase of formulation processing.

3,Is Xi'an Tihealth's Ectoine naturally derived?

Yes, our Ectoine is produced via advanced bio-fermentation processes utilizing non-GMO halophilic bacteria, ensuring a highly pure, sustainable, and nature-identical extremolyte molecule.