Oyster Mushroom Extract
Latin Name: Pleurotus ostreatus
Raw Material Alias: Pleurotus, Green Mushroom, Beifeng Mushroom, Rough-skinned Pleurotus, Hau Mushroom, Black Peony Mushroom, etc.
Detection Method: TLC/UV
Character: Brown-yellow powder
Mesh Size: Screened through 80 - 100 mesh Product Packaging: 1 kg/aluminum foil bag; 25 kg/cardboard drum Storage Conditions: In a cool, dry, dark place away from high temperatures
Validity Period: 24 months
Pharmaceutical-Grade Oyster Mushroom Extract (Pleurotus ostreatus)
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth is a specialized global B2B manufacturer of highly purified Oyster Mushroom Extract (Pleurotus ostreatus). We strictly source our raw materials from pristine ecological cultivation bases in the Qinling Mountains. This ensures the fungal biomass is exceptionally dense in active phytochemicals and entirely free from agricultural contaminants and soil-borne heavy metals.
Utilizing dynamic water extraction and advanced membrane separation technologies, we successfully isolate the mushroom's most critical therapeutic matrix: β-Glucans, Ergothioneine, and specialized Phenolic Compounds. Standardized to exacting specifications (ranging from 20% to 50% Polysaccharides), our highly soluble, fine brown powder demonstrates profound clinical efficacy in modulating lipid profiles, mitigating oxidative cellular damage, and fortifying systemic immunity. It serves as a foundational Active Pharmaceutical Ingredient (API) for premium cardiovascular-support nutraceuticals, advanced metabolic health formulas, and clinical prebiotics.
Technical Data Sheet (TDS) & Analytical Control
| Analysis Item | Target Specification | Result (Typical Batch) | Methodology |
|---|---|---|---|
| Botanical Source | Fruiting Body of Pleurotus ostreatus | Verified | Macroscopic ID |
| Total Polysaccharides | ≥ 30.0% (Customizable to 50%) | 32.4% | Phenol-Sulfuric Acid / UV |
| β-Glucan Fraction | ≥ 15.0% | 16.2% | HPLC-ELSD |
| Appearance | Brown to light brown fine powder | Complies | Visual Assessment |
| Solubility (Water 25°C) | ≥ 95% Soluble | Complies | Aqueous Dispersion |
| Loss on Drying | ≤ 5.0% | 3.8% | USP <731> |
| Heavy Metals (Pb, As) | ≤ 2.0 ppm / ≤ 1.0 ppm | < 0.5 ppm / < 0.1 ppm | ICP-MS |
| Microbiology (Total Plate) | ≤ 1000 CFU/g | < 50 CFU/g | ISO 4833-1 |
Manufacturing & Processing Excellence
Microwave-Assisted Extraction
Standard hot-water extractions often degrade heat-sensitive compounds. Tihealth employs dynamic microwave-assisted water extraction. This innovative thermodynamic process rapidly penetrates the fungal cell walls, maximizing the release and structural preservation of high-molecular-weight β-glucans and delicate phenolic compounds.
Advanced Membrane Separation
Crude oyster mushroom extracts typically contain heavy, insoluble chitins that cause sedimentation in liquids. We utilize precise membrane filtration and high-speed centrifugation. This effectively strips away inert structural fibers, resulting in a highly purified, water-soluble extract ideal for diverse dosage forms.
Strict Environmental Auditing
Fungi bio-accumulate environmental toxins. We completely mitigate this risk by sourcing exclusively from controlled ecological bases in the Qinling Mountains. Every batch is rigorously audited via ICP-MS, guaranteeing that heavy metals and pesticide residues remain strictly compliant with FDA and EU pharmacopeial limits.
Evidence-Based Pharmacological Mechanisms
Metabolic Regulation (Lipid & Glucose Control)
Oyster Mushroom extract is clinically recognized for its profound cardiovascular benefits. The specialized β-glucans and natural statin-like compounds significantly reduce serum cholesterol and triglyceride levels. Furthermore, it actively assists in modulating postprandial blood glucose and reducing glycated hemoglobin.
Cellular Antioxidant Defense (Ergothioneine)
Rich in naturally occurring Ergothioneine (L-EGT) and phenolic compounds (like Gallic and Chlorogenic acid), it functions as an aggressive free-radical scavenger. It actively mitigates cellular oxidative stress and protects mitochondrial DNA from environmental degradation and aging.
Immunomodulatory Enhancement
The high concentration of active polysaccharides acts as a powerful biological response modifier. It stimulates the innate immune system, enhancing the activity of macrophages and Natural Killer (NK) cells to establish robust systemic defense against pathogens.
Anti-Obesity (Adipocyte Inhibition)
Emerging clinical models (3T3-L1 adipocyte assays) demonstrate that the unique combination of alkaloids and flavonoids within the extract actively inhibits adipocyte differentiation, functioning as a valuable nutritional intervention for weight management therapies.
Industrial Formulation Applications
Pharmaceuticals & Nutraceuticals
The foundational API for formulating cardiovascular-support capsules, lipid-lowering tablets, and specialized dietary supplements targeting Polycystic Ovary Syndrome (PCOS).
Functional Foods & Beverages
Thanks to its excellent solubility, it integrates seamlessly into fermented energy powders, lipid-lowering meal replacements, and clear botanical elixirs.
Premium Cosmeceuticals
Utilized in high-end anti-aging serums and barrier-repair creams. The polysaccharide complexes act as powerful hydrating and soothing agents for sensitive skin.
Agricultural & Environmental Tech
Due to its potent enzymatic systems, specific fungal variants are leveraged in the manufacturing of soil remediation agents and organic biodegradable solutions.
Contract Manufacturing & Global Supply Chain
♦ Precise Active Customization
We strictly tailor the concentration of Total Polysaccharides (from 20% to highly concentrated 50% fractions) and adjust powder fineness (80-200 mesh) to perfectly match your specific formulation requirements.
♦ Traceable Quality Control
Quality is mathematically verifiable. Every batch undergoes strict cGMP-certified analysis via UV/HPLC. We provide full COAs, ensuring heavy metals, pathogens, and pesticide residues strictly comply with global pharmacopeial standards.
♦ Strict Brand Confidentiality
Secure IP protection via NDAs. We offer blind shipping, private label bulk packaging (from 1kg foil bags to 25kg sterile drums), and full FDA/EU regulatory documentation support for global customs clearance.
Packaging, Logistics & Secure Payment
Reliable B2B Supply Chain Solutions
We provide pharmaceutical-grade aseptic packaging, efficient global logistics (Air/Sea freight with dual customs clearance), and secure multi-currency payment methods to ensure seamless, oxidation-free cross-border transit for our B2B procurement partners.
Formulator & Procurement FAQ
01. Do you test specifically for β-Glucans?
Yes. While generic "polysaccharide" testing can detect inactive alpha-glucans (starches), we utilize specialized analytical methods to ensure that the core bioactive components-the immuno-stimulating β-glucans-are strictly preserved and quantified on our COA.
02. Is the extract completely water-soluble for beverage applications?
Absolutely. Through advanced membrane separation and high-speed centrifugation, we completely remove heavy insoluble fungal chitins. The resulting micro-powder disperses rapidly in water (≥95% solubility), making it perfect for functional RTD drinks without sedimentation.
03. How does Oyster Mushroom differ from Shiitake (Lentinula) extracts?
While both are excellent immune modulators, Oyster Mushroom (Pleurotus ostreatus) contains a unique matrix of natural statin-like compounds (Lovastatin) and specific polyphenols. This makes it far superior for formulations specifically targeting lipid reduction and cardiovascular health compared to Shiitake.
04. Can you guarantee the product is free from heavy metals and pathogens?
Yes. Fungi act as bio-accumulators. We proactively mitigate this risk by sourcing exclusively from ecologically controlled indoor cultivation bases in the Qinling Mountains. Every batch is verified via ICP-MS to ensure extremely low heavy metal limits (e.g., Pb ≤ 2.0 ppm).
05. What is the Minimum Order Quantity (MOQ) and packaging standard?
Our standard MOQ for mass production is 25kg, packed in heavy-duty cardboard drums lined with double sterile, nitrogen-flushed bags to prevent oxidation and moisture ingress. We also supply 1kg foil bags for pilot manufacturing and R&D trials.
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