Macleaya Cordata Extract
Product alias: Boluohui Total Alkaloids, Blood Root Alkaloids, White Quercetin Sulfate Blood Root Alkaloids, White Quercetin Sulfate
Extract source: Plant Botrytis cinerea cordate (Willd.) R.Br. with whole plant
Product specifications: Boluohui Total Alkaloids 60% (including Blood Root Alkaloids 40%, Bai Qu Cai Hong Alkaloids 20%)
Detection method: HPLC
Product Description: Orange yellow fine powder
Solubility: Water soluble
Product particle size: 95% pass through 80 mesh
Packaging specification: 1kg/bag; 25kg/cardboard drum
Shelf life: 24 months
Macleaya Cordata Extract | Sanguinarine ≥ 60% | Natural Feed Additive
Macleaya Cordata Extract (Plume Poppy) is an industry-leading botanical API globally recognized as a safe, highly effective alternative to Antibiotic Growth Promoters (AGPs) in animal husbandry. Xi'an Tihealth Biotechnology Co., Ltd. specializes in standardizing this extract to precise concentrations of isoquinoline alkaloids-specifically Sanguinarine and Chelerythrine (≥ 60.0% Total Alkaloids via HPLC).
By exerting potent, localized antimicrobial and anti-inflammatory effects within the gastrointestinal tract, our standardized extract significantly optimizes gut microbiome balance, enhances nutrient absorption (improving villi height), and boosts the Feed Conversion Ratio (FCR) in poultry, swine, and aquaculture without contributing to antimicrobial resistance.
Technical Data Sheet & Specifications
| Analytical Parameter | Xi'an Tihealth Specification |
|---|---|
| Botanical Source | Macleaya cordata (Willd.) R. Br. (Fruit/Seed Pods) |
| Standardized Actives | Total Alkaloids ≥ 60.0% (Sanguinarine ≥ 40%, Chelerythrine ≥ 15%) |
| CAS Number | 112025-60-2 (Extract) / 2447-54-3 (Sanguinarine) |
| Appearance & Odor | Orange-yellow to light orange fine powder; Characteristic odor |
| Moisture & Ash | Loss on Drying ≤ 5.0%; Sulfated Ash ≤ 5.0% |
| Heavy Metals Compliance | Total Heavy Metals ≤ 10 ppm (As ≤ 2.0 ppm, Pb ≤ 2.0 ppm) |
Industrial Packaging: Supplied in 25kg export-grade fiber drums with double-layer PE inner bags. Manufactured in an ISO9001:2015 & GMP-compliant facility ensuring strict cross-contamination control.
Gastrointestinal Modulation & AGP Replacement
Our extract acts primarily within the lumen of the gastrointestinal tract, bypassing systemic absorption to deliver localized, high-impact benefits without leaving tissue residues:
- Targeted Antimicrobial Activity: Sanguinarine disrupts the structural integrity of bacterial cell membranes and inhibits FtsZ protein assembly. It exhibits strong bactericidal properties against Gram-positive pathogens and specific Gram-negative bacteria (like E. coli and Salmonella), drastically reducing the incidence of weaning diarrhea.
- Intestinal Anti-Inflammatory Support: It actively downregulates the NF-κB signaling pathway in the intestinal mucosa. This mitigates inflammatory stress caused by dietary changes or pathogenic challenge, protecting the tight junctions of the gut lining.
- Morphological Gut Optimization: Clinical trials in poultry and swine show that dietary inclusion significantly increases villus height and the villus-to-crypt ratio, maximizing the absorptive surface area for nutrients.
Recommended Inclusion Rates (Base 60% API)
For feed mills and premix manufacturers utilizing our 60% concentrated API, the following incorporation rates are recommended (Note: Adjustments should be made based on specific premix dilutions):
| Target Species | Growth Stage | Recommended Dosage (Per Ton of Complete Feed) |
| Swine | Piglets (Weaning phase) | 1.5g - 3.0g of 60% API |
| Swine | Grower / Finisher | 1.0g - 2.0g of 60% API |
| Poultry | Broilers (Starter / Finisher) | 1.0g - 2.5g of 60% API |
| Aquaculture | Fish and Shrimp | 2.0g - 5.0g of 60% API |
Feed Manufacturing & Procurement FAQ
No. One of the greatest advantages of Macleaya Cordata extract is its zero-day withdrawal period. Because the alkaloids primarily act in the intestinal lumen and are not heavily absorbed or deposited in muscle or fat tissue, it leaves no harmful residues in meat or eggs, perfectly complying with global antibiotic-free farming regulations.
Isoquinoline alkaloids (Sanguinarine and Chelerythrine) exhibit exceptional thermostability. Our API remains completely structurally stable during standard steam conditioning and high-temperature extrusion/pelleting processes (typically 80°C - 95°C) used in modern commercial feed mills.
While the base 60% API powder is primarily designed for dry premixing into solid feed, we can supply specifically engineered water-soluble veterinary formulations (micro-emulsions or soluble salts) if you require administration via farm drinking water systems. Please specify your application method in your inquiry.
Xi'an Tihealth Biotechnology Co., Ltd. Quality Commitment: Standardized botanical extract intended strictly for professional veterinary formulation and industrial animal feed additive manufacturing.
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