Premium Dihydromyricetin (DHM) Powder | CAS 27200-12-0 | 30% HPLC | Vine Tea Extract
Botanical Source: Ampelopsis grossedentata (Leaves / Vine Tea)
CAS Number: 27200-12-0
Content Specification: 30%(HPLC)
Molecular Formula: C₁₅H₁₂O₈
Molecular Weight: 320.25 g/mol
Appearance Profile: Light yellow powder
Shelf Life: 24 Months
Dihydromyricetin (DHM) 30% Powder - Water Soluble
Manufactured by Xi'an Tihealth Biotechnology Co., Ltd.
Xi'an Tihealth Biotechnology Co., Ltd. offers a highly specialized 30% Water-Soluble Dihydromyricetin (DHM) extract, meticulously engineered for formulators requiring seamless integration into liquid-based functional products. While native DHM is naturally lipophilic and notoriously difficult to dissolve, our proprietary water-soluble matrix technology solves the primary formulation barrier for Ready-To-Drink (RTD) teas, functional beverages, and hangover-relief shots, ensuring zero turbidity and rapid dissolution kinetics.
Extracted from the pristine leaves of *Ampelopsis grossedentata* (Vine Tea), this 30% DHM specification retains the complete pharmacological potency of the parent flavonoid. It is a formidable biological agonist for accelerating alcohol-derived acetaldehyde metabolism, effectively mitigating hangover symptoms and providing powerful hepatic protection. Validated by rigorous cGMP-aligned quality controls, Tihealth's water-soluble DHM is the definitive active solution for procurement managers and product developers seeking to introduce liver-support and cellular-defense claims into their beverage and liquid nutraceutical product lines.
Technical Data Sheet (TDS) & Quality Specifications
| Analysis Parameter | Target Specification Limit | Batch Output Profile | Analytical Methodology |
|---|---|---|---|
| Biological Origin | Leaves of *Ampelopsis grossedentata* | Conforms | Microscopic / DNA Tracking |
| Assay Specification | 30.0% (Water-Soluble) | 30.5% | HPLC-UV Calibration |
| CAS Registry Number | 27200-12-0 | Confirmed | Molecular Identification |
| Appearance Parameter | Light yellow powder | Light Yellow Powder | Visual Inspection |
| Solubility | High-solubility for beverage lines | Verified Clear Solution | Physical Dispersibility Test |
| Loss on Drying | ≤ 5.0% | 3.8% | Gravimetric (USP <731>) |
| Heavy Metals (Total) | ≤ 10.0 ppm | < 5.0 ppm | ICP-MS Spectrometry |
| Total Aerobic Count | ≤ 1000 CFU/g | < 50 CFU/g | USP <61> Microbial Limit |
Advanced Processing & Quality Engineering
Water-Soluble Modification
To resolve the inherent lipophilic barrier of native DHM, we employ advanced molecular inclusion and physical dispersion engineering. This breakthrough modification transforms the hydrophobic powder into a perfectly water-compatible matrix, suitable for clear beverage applications without risk of cloudiness or particle precipitation.
Cold-Room Extraction Loop
Dihydromyricetin is chemically sensitive to prolonged exposure to industrial-level process heat, which promotes structural denaturation. Tihealth's dedicated DHM production lines utilize a completely sealed, low-thermal extraction loop, safeguarding the molecule from oxidation and preserving its native biological integrity from the vine to the final drum.
Structural Purity Auditing
Every batch undergoes rigorous high-performance liquid chromatography (HPLC) testing to differentiate target DHM from related dihydro-flavonoids. This forensic approach guarantees that your 30% DHM content is derived from verified structural consistency, preventing batch-to-batch variability and supporting seamless downstream manufacturing scaling.
Evidence-Based Mechanisms of Cellular Efficacy
Alcohol Metabolism & Liver Shield
DHM serves as a metabolic catalyst that significantly enhances the activity of key hepatic enzymes, ADH and ALDH. By accelerating the conversion of toxic acetaldehyde-the primary cause of hangovers-into non-toxic acetate, it protects hepatocytes from alcoholic toxicity and ensures faster post-consumption recovery.
Systemic ROS Scavenging & Senescence Delay
Dihydromyricetin demonstrates strong antioxidant capacity by neutralizing hydroxyl radicals and superoxide anions. This biological scavenger action reduces systemic oxidative stress, protecting nuclear DNA and lipid bilayers from environmental degradation, effectively delaying cellular aging.
Anti-Inflammatory & Cardiovascular Support
By down-regulating key pro-inflammatory pathways (including NF-κB signaling), it mitigates cellular inflammation. Furthermore, it supports cardiovascular health by improving systemic circulatory dynamics and mitigating oxidative damage to vascular endothelium.
Natural Bacteriostatic Potential
Beyond its metabolic properties, DHM exhibits natural bacteriostatic effects. This makes it an ideal functional ingredient for wellness products aimed at maintaining overall systemic health, immune stabilization, and maintaining microbial balance.
Targeted Industrial Applications
Hangover & Liver-Health Supplements
The critical functional ingredient for hangover-relief tablets, detox pills, and liver-protection capsules seeking high biological bioavailability.
Functional Beverage Line-Extensions
Utilizing our 30% and 50% water-soluble specifications to enable clear, high-concentration DHM shots, functional teas, and metabolic health beverages.
Advanced Clinical API Research
Actively pursued in clinical research as a versatile drug candidate for investigating liver recovery pathways, metabolic disease regulation, and anti-tumor therapeutic research.
Metabolic & Cardiovascular Stacks
Formulated into metabolic health blends, where its potent antioxidant mechanisms complement cardiovascular support regimes and long-term cellular health initiatives.
Contract Manufacturing & Global Supply Chain Assurance
♦ Targeted Specification Portfolios
We align our extraction outputs directly with your manufacturing lines. Whether you require standard aglycone for encapsulation or highly engineered water-soluble matrices for beverages, we ensure absolute physical compatibility.
♦ Trace Analytical Verification
Quality is documented with mathematical certainty. Every shipment comes with a comprehensive Certificate of Analysis (COA) detailing precise HPLC quantification, ensuring our products clear any stringent third-party quality control and audit.
♦ Secure Commercial Fulfillment
We protect your intellectual proprietary secrets with absolute security. We support advanced contract manufacturing and issue full cGMP-compliant technical documentation packages to guarantee immediate custom clearance globally.
Packaging, Logistics & Secure Payment
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