Vitamin D3 Powder

Vitamin D3 Powder

Product Name: Vitamin D3
Product alias: Cholecalciferol
Content specifications: 400IU (International Units), 600IU, 1000IU -100000IU
Detection method: HPLC
Number of Contents: 80-100
Appearance: Colorless needle shaped crystals or white crystalline powder
Product use: Calcium absorption promotion, bone health maintenance, immune system regulation, etc
Product packaging: 1KG/aluminum foil bag; 25KG/cardboard drum
Product storage: Store in a dry and cool place, away from sunlight and high temperatures
Shelf life: 24 months
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Characteristics

 

Characteristic classification

Description

Chemical structure

Vitamin D3 is a fat soluble vitamin belonging to the steroid class, with one cyclopentane tetrahydronaphthyl group and two side chains: octadecadienoic acid and octadecadienoic acid.

Bioactive form

1 α, 25 dihydroxyvitamin D3 (1,25 (OH) 2D3) is the active form of vitamin D3 and plays an important regulatory role in calcium and phosphorus metabolism.

Source

It can be synthesized through the skin under sunlight or obtained from foods such as cod liver oil and egg yolks.

Function

Promote the absorption of calcium and phosphorus, maintain bone health, regulate the immune system, reduce inflammation, prevent various diseases such as rickets, osteoporosis, autoimmune diseases, etc.

Metabolic pathway

In the kidneys, 25 hydroxyvitamin D3 is converted into the active form 1 α, 25 dihydroxyvitamin D3.

Physiological functions

regulate cell proliferation, differentiation, and apoptosis, enhance immune function, protect cardiovascular health, and support mental health.

Symptoms of deficiency

Vitamin D3 deficiency may lead to rickets, osteomalacia, osteoporosis, muscle weakness, and bone pain.

Excessive risk

Long term excessive intake may lead to kidney stones and kidney calcification. It is recommended that adults consume no more than 100 micrograms per day and children consume no more than 50 micrograms per day.

Application

Widely used in dietary supplements, fortified foods, and pharmaceutical products to increase vitamin D levels in the body.

Advantages

 

The advantages of vitamin D3 are mainly reflected in the following aspects:

1. Bone health:

Vitamin D3 is a key factor in maintaining bone health, as it promotes the absorption of calcium and phosphorus, thereby aiding in bone mineralization and increased density.

This is particularly important for the growth and development of children and the prevention of osteoporosis in the elderly.

2. Immune system support:

Vitamin D3 is crucial for the normal functioning of the immune system, regulating immune responses and reducing the risk of infections and autoimmune diseases.

It enhances the body's disease resistance by strengthening the function of immune cells such as T cells and macrophages.

3. Cardiovascular health:

Research has shown that vitamin D3 helps reduce the risk of cardiovascular disease by regulating blood pressure, reducing vascular inflammation, and controlling cholesterol levels to protect heart health.

4. Psychological health:

Vitamin D3 is closely related to emotional regulation, and high levels of vitamin D3 are associated with reducing depressive symptoms.

It may improve mood by affecting the synthesis of certain neurotransmitters in the brain.

5. Cancer prevention:

Adequate vitamin D3 levels are associated with a reduced risk of certain types of cancer, including breast cancer, prostate, and colon cancers.

Vitamin D3 reduces cancer risk by inhibiting cell proliferation and anti-inflammatory effects.

6. Weight management:

Vitamin D3 is associated with appetite suppression. Studies have shown that adequate intake of vitamin D3 can promote weight loss and reduce the risk of weight related diseases.

7. Muscle function:

Vitamin D3 is crucial for muscle function, helping to reduce the risk of muscle weakness and falls, especially beneficial for the elderly.

8. Skin Health:

Vitamin D3 is involved in skin health, helping to reduce the risk of skin conditions, supporting skin wound healing, and preventing certain skin diseases.

9. Other benefits:

Vitamin D3 may also have a positive impact on diabetes management, athlete performance, longevity, hair health and anti-aging.

Vitamin D3 has significant benefits in bone health, immune system, cardiovascular health, mental health, cancer prevention, weight management, muscle function, skin health, and is an important nutrient for maintaining overall health.

Function

Vitamin D3 is a fat soluble vitamin with multiple important physiological functions and applications. The following is a detailed description of the efficacy and application of vitamin D3:

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1. Promote the absorption of calcium and phosphorus:

Vitamin D3 promotes the absorption of calcium and phosphorus by the small intestinal mucosa, maintains normal levels of calcium and phosphorus in the plasma, and thus supports bone health and dental integrity.

2. Regulating immune function:

Vitamin D3 can enhance the body's immunity, promote the differentiation and maturation of T lymphocytes, thereby helping to resist infections and autoimmune diseases.

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3. Anti inflammatory effect:

Vitamin D3 has significant anti-inflammatory properties, which can inhibit the production of inflammatory mediators such as TNF - α and NF - κ B, alleviate chronic inflammatory symptoms, and be beneficial for diseases such as rheumatoid arthritis and inflammatory bowel disease

4. Cardiovascular health:

Vitamin D3 may reduce the risk of cardiovascular disease by regulating blood pressure and maintaining healthy vascular function.

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5. Cancer prevention:

Adequate vitamin D3 levels may reduce the risk of certain types of cancer, including breast cancer, prostate and colon cancers.

6. Emotional and mental health:

Vitamin D3 is associated with emotional regulation and mental health, and may help reduce the risk of depression and improve overall well-being.

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7. Muscle function:

Vitamin D3 is crucial for muscle function, helping to reduce the risk of muscle weakness and falls, especially beneficial for the elderly.

8. Weight management:

Vitamin D3 may be related to the regulation of weight loss and metabolic processes, and low vitamin D levels are associated with obesity.

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9. Dental health:

Adequate levels of vitamin D3 are associated with better dental health, reducing the risk of gum disease and dental caries.

10. Skin Health:

Vitamin D3 is involved in skin health, helping to reduce the risk of skin conditions, supporting skin wound healing, and preventing certain skin diseases.

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Application

Vitamin D3 is a fat soluble vitamin with multiple important physiological functions and applications.

The following is a detailed description of the efficacy and application of vitamin D3:

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1. Treatment of bone metabolism disorders:

Vitamin D3 is used to treat bone metabolism diseases such as rickets, osteomalacia, and infantile tetany.

2. Management of autoimmune diseases:

Vitamin D3 plays a role in reducing the risk of autoimmune diseases such as multiple sclerosis and type 1 diabetes and helping to manage these diseases

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3. Prevention of cardiovascular diseases:

Vitamin D3 is used for the prevention and management of cardiovascular diseases by regulating blood pressure and maintaining healthy vascular function.

4. Tumor prevention and treatment:

Vitamin D3 has potential in tumor prevention and treatment, especially in the prevention of breast cancer, prostate cancer and colon cancer

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5. Management of chronic kidney disease:

Vitamin D3 plays a role in the management of chronic kidney disease by regulating calcium and phosphorus metabolism and anti proliferative factors in patients.

6. Neuroprotection:

Vitamin D3 reduces or prevents the occurrence and development of various neurological diseases by inhibiting inflammatory factors and oxidative stress.

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7. Pulmonary disease management:

Vitamin D3 plays a key role in lung immune regulation, by inhibiting the secretion of inflammatory mediators and enhancing the barrier function of respiratory epithelial cells, for the management of asthma and other lung diseases.

8. Intervention for childhood obesity:

Vitamin D3 has important value in the diagnosis and intervention of childhood obesity, and moderate supplementation of vitamin D can help improve childhood obesity and glucose and lipid metabolism disorders.

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Vitamin D3 has significant effects in promoting calcium and phosphorus absorption, regulating immune function, anti-inflammatory, cardiovascular health, cancer prevention, emotional management, muscle function, weight management, dental health, skin health, etc. It is widely used in bone metabolism diseases, autoimmune diseases, cardiovascular diseases, tumor prevention, chronic kidney disease, neuroprotection, lung diseases, and interventions for childhood obesity.

Production details

The production of vitamin D3 involves various methods, mainly including chemical synthesis and microbial transformation.

The following is a detailed production process:

Chemical synthesis method

1. Raw material preparation:

The main raw material is 7-dehydrocholesterol, usually extracted from animal brain marrow or lanolin.

7-dehydrocholesterol can also be extracted from vegetable oil or yeast.

2. Photochemical ring opening reaction:

Dissolve 7-dehydrocholesterol in ethanol or other solvents (such as chloroform or cyclohexane), and then perform a ring opening reaction by irradiating with ultraviolet light.

The reaction solution is concentrated, frozen, filtered, and the filtrate is concentrated to dryness under reduced pressure with nitrogen to obtain crude vitamin D3 solution.

3. Refining process:

The crude vitamin D3 solution is further refined to remove impurities and obtain high-purity vitamin D3.

4. Other chemical methods:

Bromination/dehydrobromination method: 7-dehydrocholesterol is synthesized through steps such as esterification, catalytic oxidation, hydrazone formation, and dehydrozone reaction, followed by photochemical synthesis to produce VD3.

Redox method: using similar raw materials and steps, but with higher yield.

Microbial transformation method

1. Strain selection:

Microorganisms such as Rhodococcus, Streptomyces, Pseudo Nocardia sp., and Mycobacteria are used.

2. Fermentation process:

During the fermentation process, microorganisms convert 7-dehydrocholesterol into vitamin D3 through their endogenous enzyme system.

This process has mild conditions, strong specificity, and fewer reaction steps.

3. Product separation and purification:

The fermentation broth contains a lot of impurities, which need to be removed through separation and purification processes to obtain high-purity vitamin D3.

Application of New Technologies

Ultra fast laser microchannel technology:

Using ultrafast laser to carve microchannels on glass, these microchannels provide excellent transparency for ultraviolet radiation, thereby increasing the yield of VD3 and reducing production costs.

This technology has achieved continuous flow production, increasing output by over 20% and significantly improving production efficiency.

Biosynthetic pathway

In vivo synthesis:

Vitamin D3 mainly comes from the light conversion of 7-dehydrocholesterol under ultraviolet B (UVB) irradiation.

In the liver, pre vitamin D3 is further metabolized into Cholecalciferol, also known as active vitamin D3.

Vitamin D3 then enters the kidneys, where it is further metabolized into 25 hydroxyvitamin D3, which is one of the most active forms in the body.

summary

There are various methods for producing vitamin D3, including chemical synthesis and microbial transformation.

Although chemical synthesis is complex and heavily polluting, it is still the main production method at present.

The microbial transformation method has potential application prospects due to its mild conditions and strong specificity.

New technologies such as ultrafast laser microchannel technology provide new solutions for improving production efficiency and reducing costs.

 

Packaging

 

Solid powder packaging

Weight

Packaging

Weight

Packaging

Weight

Packaging

1kg

Aluminum foil bag

5kg

Aluminum foil bag

25kg

Cardboard bucket

           

Services

 

 

Logistics services:

As a biotechnology company, Tihealth Biotechnology Company provides international cross-border e-commerce logistics services with the following characteristics:

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1. International express delivery services

International express giants such as DHL, FedEx, and UPS provide fast and reliable transportation services.

Usually it can be delivered within 5-7 working days, which can meet the transportation requirements for goods with high timeliness.

These express delivery services have a wide range of branches worldwide, facilitating the sending and receiving of packages, and providing package tracking services where both sellers and buyers can view the real-time status of their packages.

 

2. Dedicated logistics services

This is a logistics service specifically designed for a specific country or region.

For example, there is a dedicated e-commerce line from China to Europe.

Its advantage lies in providing fast transportation and more precise logistics solutions for specific areas.

The transportation time is approximately 7-15 days, which is very attractive to sellers with a concentrated target market. Moreover, in some cases, the shipping cost of dedicated logistics in specific areas is more competitive than international express delivery.

 

3. Support dual clearing service

Provide import and export customs clearance services according to customer needs.

It can conveniently and quickly save a lot of time and energy, effectively reducing problems that may arise during the customs clearance process of goods

 

OEM Services

1. Customized production:

Customized production of products can be carried out based on customers' brand needs and product design requirements, utilizing our own production equipment, technology, and processes. For example, if a customer is a fitness brand and wants to launch a sports nutrition supplement with specific effects, Xi'an Tihealth Biotechnology Co., Ltd. can produce it according to the formula, specifications, packaging design, etc. provided by the customer.

 

2. Quality control:

Xi'an Tihealth Biotechnology Co., Ltd. has established a strict quality control system in accordance with requirements to ensure that the OEM products produced meet customer quality standards and comply with relevant regulatory requirements.

Strictly control the procurement of raw materials, monitoring of production processes, and inspection of finished products to ensure the stability and safety of product quality.

 

3. Brand confidentiality:

In OEM cooperation, we will strictly protect customers' brand information and trade secrets.

Take measures such as signing confidentiality agreements and restricting internal personnel access to prevent the leakage of confidential information such as customer brand designs and formulas.

Regulatory consultation and support: In the field of health products, regulatory requirements are relatively strict.

Xi'an Tihealth Biotechnology Co., Ltd. may provide customers with relevant regulatory consulting services to help them understand and comply with national and local laws and regulations, ensuring the legal and compliant sale of products.

Provide professional guidance and support in product registration, filing, and other aspects.

 

If you want to know more accurate and detailed information, it is recommended to directly contact Xi'an Tihealth Biotechnology Co., Ltd. for consultation.

 

 

 

Payment Methods

 

 

product-1597-400

Delivery methods

 

 

Quantity

<25kg

<100kg

>100kg

>1000kg

Delivery Time

3Day

3Day

7Day

15Day

 


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