High-Purity β-Nicotinamide Mononucleotide (NMN) API | CAS 1094-61-7

β-Nicotinamide Mononucleotide (NMN, CAS No. 1094-61-7) is a pivotal bioactive nucleotide and the direct, rate-limiting precursor to Nicotinamide Adenine Dinucleotide (NAD+). Manufactured under stringent pharmaceutical-grade protocols, Xi'an Tihealth utilizes advanced enzymatic biocatalysis technology to produce ultra-pure NMN powder. This targeted synthetic route ensures 100% specific stereoisomeric purity (exclusively the biologically active β-form) while eliminating harsh chemical solvent residues. With an HPLC-validated assay of ≥99.0%, our NMN API serves as the foundational active ingredient for next-generation longevity therapeutics, premium dietary supplements, and advanced cellular-repair cosmetics.

We guarantee exceptional batch-to-batch consistency and stability. The following parameters represent our standard release criteria for API-grade NMN:

NMN fundamentally operates through the targeted replenishment of intracellular NAD+ pools, governing critical metabolic and genomic pathways:

• Direct NAD+ Precursor: NMN utilizes specific membrane transporters (e.g., Slc12a8) to rapidly enter the cytoplasm, where it is seamlessly synthesized into NAD+, overcoming the rate-limiting bottlenecks associated with other precursors like NAM or NR.
• Sirtuin Activation: Elevated NAD+ levels act as the essential substrate for Sirtuins (SIRT1-SIRT7, the "longevity proteins"), triggering downstream cascades that regulate mitochondrial biogenesis, oxidative stress resistance, and cellular senescence.
• Genomic Stability (PARP1 Support): NAD+ is structurally consumed by Poly (ADP-ribose) polymerases (PARPs) during DNA damage detection and repair. NMN supplementation prevents NAD+ depletion, ensuring continuous genomic integrity.

• Pharmaceutical R&D: Investigational API for therapies targeting age-related metabolic syndrome, neurodegeneration, and ischemia-reperfusion injury.
• Premium Nutraceuticals: The gold-standard active ingredient for high-end longevity supplements (capsules, sublingual tablets, and liposomal liquids) designed to combat physiological aging and cellular fatigue.
• Advanced Dermo-Cosmetics: Incorporated into luxury topical formulations to enhance epidermal NAD+ levels, boosting localized ATP production for intensive wrinkle reduction and photo-aging repair.

Xi'an Tihealth exclusively utilizes advanced enzymatic biocatalysis. This eco-friendly, highly controlled process completely avoids toxic heavy metal catalysts and harsh chemical solvents, yielding a safer, pharmaceutical-grade product with 100% β-isomer purity.

2,What is the difference between β-NMN and α-NMN?

Only the β-conformation of NMN is biologically recognized and utilized by the human body to synthesize NAD+. α-NMN has no known biological value and may act as an impurity. Our analytical testing strictly ensures 0% α-isomer content.

3,Can you supply different bulk densities for capsule vs. tablet formulations?

Yes. We understand the physical flowability requirements of nutraceutical manufacturing. We can provide customized particle sizes and bulk densities (high-density vs. low-density powder) tailored to your specific encapsulation or tableting machinery.