L-Theanine Extract Powder | Pure L-Enantiomer | CAS 3081-61-6
Product Description

Xi'an Tihealth L-Theanine Powder (Premium Grade)
Xi'an Tihealth supplies high-purity L-Theanine (CAS 3081-61-6), a unique non-proteinogenic amino acid found predominantly in Camellia sinensis (green tea). Accounting for over 50% of the total free amino acids in tea leaves, L-Theanine is responsible for the characteristic umami (sweet and savory) flavor profile of premium shaded teas (like Matcha).
As a highly water-soluble white crystalline powder, our L-Theanine is engineered to ensure strict chiral purity (exclusively the L-enantiomer) for maximum biological efficacy. It is globally recognized for its ability to cross the blood-brain barrier, promoting "focused relaxation" without inducing drowsiness, making it a staple ingredient in advanced nootropics and functional beverages.
Chemical & Physical Properties
- Product Name: L-Theanine
- CAS Number: 3081-61-6
- Chemical Formula: C7H14N2O3
- Molecular Weight: 174.20 g/mol
- Synonyms: N-Ethyl-L-glutamine; L-Glutamic acid γ-(ethylamide)
- Appearance: White acicular (needle-like) crystalline powder; readily soluble in water.
Pharmacokinetics & Clinical Efficacy
Absorption & Metabolism: Upon oral ingestion, L-Theanine is rapidly absorbed through the intestinal brush border and enters systemic circulation. Peak concentrations in blood and the liver decline after 1 hour, whereas brain concentrations peak at approximately 5 hours. It is metabolized in the kidneys and excreted via urine, completely clearing the system within 24 hours.
Neurotransmitter Modulation: It actively crosses the blood-brain barrier, influencing the release and metabolism of critical neurotransmitters like dopamine and serotonin. This mechanism is believed to play a role in regulating mood and preventing certain neurotransmitter-mediated neurological disorders.
Alpha Brain Wave Promotion: Upregulates alpha (α) wave activity, a state correlated with relaxed alertness. It mitigates the stimulatory effects of caffeine, explaining why drinking tea induces a peaceful, calm state rather than nervous excitation.
Formulation Applications
- Premenstrual Syndrome (PMS) Relief: Clinical trials indicate the calming effects of L-Theanine significantly alleviate both the psychological (irritability, depression, restlessness) and physical (fatigue, sleep disturbance, lower abdominal pain) symptoms associated with PMS in women aged 25-45.
- Cognitive & Nootropic Stacks: Proven in animal models to improve memory and learning capacity. In human formulations, it is the gold standard for pairing with Caffeine (typically a 2:1 ratio) to blunt "jitters" while amplifying cognitive clarity and sustained attention.
- Stress Management & Functional Beverages: Ideal for daytime relaxation products and "calm focus" RTD beverages due to its high aqueous solubility, thermal stability, and pleasant, slightly sweet taste profile.
Certificate of Analysis Summary
| Test Parameter | Acceptance Criteria |
|---|---|
| Purity (HPLC) | ≥ 99.0% |
| Specific Rotation [a]D20 | +7.5° to +8.5° (Confirms L-isomer) |
| pH Value (1% solution) | 5.0 - 6.0 |
| Residue on Ignition | ≤ 0.2% |
Technical FAQ
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