L-Theanine Extract Powder | Pure L-Enantiomer | CAS 3081-61-6

L-Theanine Extract Powder | Pure L-Enantiomer | CAS 3081-61-6

Products Description Xi'an Tihealth L-Theanine Powder Xi'an Tihealth supplies pharmaceutical and food-grade L-Theanine (CAS 3081-61-6) , a unique neuroactive amino acid originally identified in Camellia sinensis (green tea). Our L-Theanine is engineered to ensure strict chiral purity...
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Product Description

L-Theanine Extract Powder
Xi'an Tihealth L-Theanine Powder (Premium Grade)

Xi'an Tihealth supplies high-purity L-Theanine (CAS 3081-61-6), a unique non-proteinogenic amino acid found predominantly in Camellia sinensis (green tea). Accounting for over 50% of the total free amino acids in tea leaves, L-Theanine is responsible for the characteristic umami (sweet and savory) flavor profile of premium shaded teas (like Matcha).

As a highly water-soluble white crystalline powder, our L-Theanine is engineered to ensure strict chiral purity (exclusively the L-enantiomer) for maximum biological efficacy. It is globally recognized for its ability to cross the blood-brain barrier, promoting "focused relaxation" without inducing drowsiness, making it a staple ingredient in advanced nootropics and functional beverages.

Chemical & Physical Properties

  • Product Name: L-Theanine
  • CAS Number: 3081-61-6
  • Chemical Formula: C7H14N2O3
  • Molecular Weight: 174.20 g/mol
  • Synonyms: N-Ethyl-L-glutamine; L-Glutamic acid γ-(ethylamide)
  • Appearance: White acicular (needle-like) crystalline powder; readily soluble in water.

Pharmacokinetics & Clinical Efficacy

Absorption & Metabolism: Upon oral ingestion, L-Theanine is rapidly absorbed through the intestinal brush border and enters systemic circulation. Peak concentrations in blood and the liver decline after 1 hour, whereas brain concentrations peak at approximately 5 hours. It is metabolized in the kidneys and excreted via urine, completely clearing the system within 24 hours.

Neurotransmitter Modulation: It actively crosses the blood-brain barrier, influencing the release and metabolism of critical neurotransmitters like dopamine and serotonin. This mechanism is believed to play a role in regulating mood and preventing certain neurotransmitter-mediated neurological disorders.

Alpha Brain Wave Promotion: Upregulates alpha (α) wave activity, a state correlated with relaxed alertness. It mitigates the stimulatory effects of caffeine, explaining why drinking tea induces a peaceful, calm state rather than nervous excitation.

Formulation Applications

  • Premenstrual Syndrome (PMS) Relief: Clinical trials indicate the calming effects of L-Theanine significantly alleviate both the psychological (irritability, depression, restlessness) and physical (fatigue, sleep disturbance, lower abdominal pain) symptoms associated with PMS in women aged 25-45.
  • Cognitive & Nootropic Stacks: Proven in animal models to improve memory and learning capacity. In human formulations, it is the gold standard for pairing with Caffeine (typically a 2:1 ratio) to blunt "jitters" while amplifying cognitive clarity and sustained attention.
  • Stress Management & Functional Beverages: Ideal for daytime relaxation products and "calm focus" RTD beverages due to its high aqueous solubility, thermal stability, and pleasant, slightly sweet taste profile.

Certificate of Analysis Summary

Test Parameter Acceptance Criteria
Purity (HPLC) ≥ 99.0%
Specific Rotation [a]D20 +7.5° to +8.5° (Confirms L-isomer)
pH Value (1% solution) 5.0 - 6.0
Residue on Ignition ≤ 0.2%

Technical FAQ

Q: Why is chiral purity (L-enantiomer) critical for Theanine?
Only the L-enantiomer of Theanine possesses the desired neuroactive properties and the ability to effectively cross the Blood-Brain Barrier (BBB). D-Theanine acts as a competitive inhibitor and reduces efficacy. Tihealth guarantees strictly controlled L-isomer purity.
Q: How does L-Theanine interact with Caffeine in formulations?
L-Theanine acts synergistically with caffeine. While caffeine stimulates the central nervous system, L-Theanine promotes relaxation by increasing alpha brain waves and GABA levels. This combination provides smooth, sustained energy and focus without the rapid crash or anxiety often associated with caffeine alone.

Looking for premium L-Theanine for your next formulation?

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