High Purity γ-Aminobutyric Acid (GABA) API Powder | CAS 56-12-2
Products Description

Xi'an Tihealth γ-Aminobutyric Acid (GABA)
Xi'an Tihealth provides premium-grade γ-Aminobutyric Acid (GABA, CAS 56-12-2), produced via advanced microbial fermentation (Lactobacillus) to ensure high bio-affinity and safety. As the primary inhibitory neurotransmitter in the mammalian central nervous system, GABA acts as the brain's critical "braking system," downregulating neuronal excitability.
Our bulk GABA powder features an exceptional assay purity of ≥ 99.0% (HPLC) with excellent aqueous solubility. It is the cornerstone ingredient for advanced nutraceuticals targeting sleep architecture improvement, anxiolytic (anti-anxiety) support, and autonomic nervous system regulation. Supplied with comprehensive ISO and GMP-compliant dossiers.
Mechanism of Action
1. Neuronal Inhibition: GABA binds to specific post-synaptic receptors (GABA-A and GABA-B), opening ion channels that hyperpolarize the cell membrane, effectively counteracting excitatory neurotransmitters like glutamate.
2. Gut-Brain Axis Modulation: Exogenous GABA interacts with the enteric nervous system (ENS). Evidence suggests it modulates the autonomic nervous system via the vagus nerve, initiating systemic relaxation and mitigating somatic stress responses without necessitating direct blood-brain barrier (BBB) penetration.
Formulation Applications
- Sleep Support Nutraceuticals: Formulated in capsules and functional shots to decrease sleep latency and improve REM sleep quality.
- Stress Management Formulations: Synergistic stacking with Magnesium and L-Theanine for acute anxiolytic effect and mood stabilization.
- Functional Foods & Beverages: Highly soluble profile ideal for "relaxation" RTD (Ready-To-Drink) beverages and gummies.
Certificate of Analysis Summary
| Test Parameter | Acceptance Criteria |
|---|---|
| Assay (GABA Content) | ≥ 99.0% (HPLC) |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals (Pb/As/Cd/Hg) | ≤ 10.0 ppm Total |
| Microbiology (Total Plate Count) | ≤ 1000 CFU/g |
Technical FAQ
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