Griffonia Seed Extract (5-HTP 98% HPLC) | Natural Serotonin Precursor | CAS 4350-09-8
Product Description
Xi'an Tihealth Griffonia Seed Extract (5-HTP)
Xi'an Tihealth provides high-purity Griffonia Seed Extract, standardized to contain ≥ 98.0% 5-Hydroxytryptophan (5-HTP) via HPLC. Sourced from the seeds of Griffonia simplicifolia, our ingredient is a 100% natural, botanically derived precursor to serotonin, meeting the stringent purity requirements of premium food and nutraceutical manufacturers.
Unlike synthetic or fermented alternatives, our botanical extraction process ensures a clean profile free from "Peak X" contaminants. It is the raw material of choice for formulators requiring precise dosage control, consistent chemical stability, and high aqueous compatibility in cognitive-support and sleep-health applications.
Chemical & Physical Properties
- Active Component: 5-Hydroxytryptophan (5-HTP)
- Botanical Source: Griffonia simplicifolia Seeds
- CAS Number: 4350-09-8
- Molecular Formula: C11H12N2O3
- Molecular Weight: 220.23 g/mol
Mechanism of Action
1. Direct Serotonin Precursor: 5-HTP bypasses the rate-limiting step of tryptophan hydroxylase, ensuring efficient conversion into Serotonin (5-HT). This enhances central nervous system neurotransmission essential for emotional regulation.
2. Bioavailability Path: Possessing high affinity for transport systems across the blood-brain barrier (BBB), it is the most effective natural substrate for stimulating central nervous system serotonin levels.
3. Circadian Support: Elevated serotonin levels provide the foundational substrate for the pineal gland's synthesis of Melatonin, supporting natural sleep-wake cycle regulation.
Formulation Applications
- Mood & Emotional Wellness: Ideal for "clean-label" mood support supplements requiring natural, effective precursors.
- Sleep & Stress Architecture: Highly effective in stacks targeting sleep quality and diurnal stress mitigation.
- Weight Management: Supports appetite suppression via serotonin-linked satiety signaling, perfect for advanced weight management formulation stacks.
Certificate of Analysis Summary (98% HPLC)
| Test Parameter | Acceptance Criteria |
|---|---|
| Purity (5-HTP by HPLC) | ≥ 98.0% |
| Peak X Impurity | Not Detected (ND) |
| Appearance | White to off-white fine powder |
| Loss on Drying | ≤ 1.0% |
| Heavy Metals (Pb, As, Cd, Hg) | ≤ 10.0 ppm Total |
Technical FAQ
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