Somatostatin Powder Cas No.51110-01-1
Source: Synthetic
Specification: ≥98%
CAS No.: 51110-01-1
Molecular Formula: C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight: 1637.9 g/mol
Testing Method: HPLC
Active Ingredient: Somatostatin (Tetradecapeptide)
Characteristics: White to off-white lyophilized powder
Packaging: Sealed transparent glass vial with inner liner, or customized packaging
Storage Condition: Store sealed under low temperature, protected from light, and in dry conditions
Shelf Life: 24 months
Declaration of Use: This product is intended for industrial use or scientific research only.
Products Description
The somatostatin active pharmaceutical ingredient (Somatostatin API) we supply is a high-purity lyophilised powder produced via synthetic processes, with HPLC purity consistently maintained above 98%. This product strictly adheres to pharmaceutical-grade quality standards, fully meeting core requirements for medical applications.
Our product has become a trusted API supplier for numerous pharmaceutical enterprises worldwide. We offer flexible packaging solutions ranging from 10mg to 1kg according to customer requirements. We welcome enquiries for collaboration and shall provide you with highly competitive product solutions.
Pharmacological Action
Somatostatin is a cyclic tetradecapeptide hormone with broad inhibitory effects. Its main pharmacological action involves strongly suppressing the secretion and release of multiple endocrine and exocrine hormones. It notably inhibits growth hormone, thyroid-stimulating hormone, insulin, glucagon, gastric acid, gastrin, pepsin, and gastrointestinal motility across various systems, demonstrating significant multifunctional negative regulation.
Mechanism of Action
Somatostatin acts by specifically binding to somatostatin receptors on target cell membranes. Five subtypes are currently known. These receptors are coupled to G proteins; when somatostatin binds, they primarily inhibit adenylate cyclase activity, reduce intracellular cAMP levels, and modulate calcium and potassium ion channels. Ultimately, these actions achieve a series series of biological effects, including inhibition of hormone secretion, reduction of exocrine gland output, and slowing of intestinal peristalsis.
Product Efficacy
Based on its extensive inhibitory effects, somatostatin APIs deliver the following key therapeutic benefits when formulated into finished drugs:
Highly effective suppression effective suppression of hormone secretion: Rapidly and effectively curbs pathological overproduction of various pituitary and pancreatic hormones.
Comprehensive digestive system inhibition: Significantly reduces the secretion of gastric acid, pancreatic juice, and other digestive fluids while decreasing gastrointestinal pressure and blood flow.
Product Applications
Pharmaceutical products manufactured from somatostatin API have critical clinical applications clinical applications, primarily including:
Control of acute gastrointestinal hemorrhage: Especially effective in esophageal variceal bleeding and stress ulcer bleeding, achieving hemostasis by reducing splanchnic blood flow.
Management of symptoms related to endocrine tumors: Used to alleviate severe diarrhea, flushing, and other symptoms caused by neuroendocrine tumors originating from the pancreas and gastrointestinal tract.
Adjuvant therapy in perioperative management: Administered after pancreatic, biliary, or intestinal surgeries to prevent and treat complications like pancreatic fistula and enteric fistula. It also inhibits pancreatic secretion, making it useful as adjunctive therapy in severe acute pancreatitis.
Treatment of acromegaly: Employed to suppress abnormally elevated serum growth hormone and IGF-1 levels in affected patients.
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