GHK-Cu Copper Tripeptide-1 API | Low Free Copper Cosmetic Powder | CAS 89030-95-5
Product source: Synthetic (Chemical synthesis, high-purity grade)
Content specification: ≥ 98% (HPLC)
CAS number: 89030-95-5
Testing method: HPLC
Active ingredient: Copper Tripeptide-1 (GHK-Cu)
Appearance: Light blue to blue crystalline powder (fine, uniform, no granular)
Product packaging: 1kg/bag; 25kg/drum
Product storage: Sealed, cool, dry and dark place, avoid moisture, heat and direct sunlight
Shelf life: 24 months
GHK-Cu Copper Tripeptide-1 API | CAS 89030-95-5 | ≥98%
Copper Tripeptide-1 (GHK-Cu) is a high-activity signaling peptide complex extensively utilized in advanced dermatological and cosmetic formulations. Manufactured by Xi'an Tihealth Biotechnology Co., Ltd., this cosmetic-grade API is synthesized through rigorous chemical pathways to yield a high-purity (≥ 98.0% HPLC) complex. It functions primarily by stimulating the synthesis of collagen and elastin, and by modulating matrix metalloproteinases (MMPs) to support extracellular matrix remodeling.
⚠️ REGULATORY COMPLIANCE & RESEARCH USE ONLY (RUO)
Industrial Application: This high-purity GHK-Cu is supplied exclusively as a raw material API powder for professional laboratory research and industrial cosmetic manufacturing. It is NOT a finished retail product for direct consumer application.
Formulation Guidelines & Stability Control
A critical challenge in cosmetic manufacturing is the premature dissociation of the copper ion from the GHK sequence, leading to product discoloration and loss of efficacy. Xi'an Tihealth's API-grade GHK-Cu is engineered with ultra-low free copper ions to maximize baseline stability. Formulators must adhere to the following protocols:
- Polymer Compatibility: Strictly avoid anionic thickeners such as Carbomer (polyacrylic acid). The carboxylic acid groups will competitively chelate the copper, resulting in immediate viscosity collapse and a shift to a pale green hue. Recommended Alternatives: Non-ionic or cationic rheology modifiers (e.g., Hydroxyethylcellulose, Xanthan Gum).
- Chelating Agents: Do not include EDTA or its derivatives in the aqueous phase, as its binding affinity for copper exceeds that of the tripeptide.
- pH Parameters: Maintain the final formulation pH strictly within the 5.5 to 7.0 range. Acidic environments (< 5.0) induce rapid dissociation of the copper complex.
- Redox Reactions: Isolate from strong reducing agents like Ascorbic Acid (Vitamin C), which may reduce Cu2+ to Cu+, altering the molecular structure.
Technical Data Sheet & Logistics Specifications
| Analytical Parameter | Xi'an Tihealth Specification |
|---|---|
| Product Name | GHK-Cu / Copper Tripeptide-1 |
| CAS Number | 89030-95-5 |
| Source / Production | Synthetic (Chemical Synthesis) |
| Assay Purity (HPLC) | ≥ 98.0% |
| Appearance | Characteristic blue powder |
Packaging & Storage: Supplied in 1kg sealed aluminum foil bags or 25kg export-grade fiber drums. Must be stored in tightly sealed original containers. Keep in a cool, dry, and dark facility. Shelf life is 24 months from the date of manufacture.
Frequently Asked Questions (R&D and Procurement)
A shift from blue to green or clear indicates that the copper ion has dissociated from the GHK peptide. This is typically caused by competitive chelation from ingredients like EDTA, acidic pH levels, or interactions with anionic polymers like Carbomer. Using Xi'an Tihealth's high-purity GHK-Cu with low free-copper ensures a more stable baseline, but strict adherence to compatible excipients is mandatory.
Is your Copper Tripeptide-1 suitable for microneedling (mesotherapy) products?
Yes. Our GHK-Cu is synthesized to highly rigorous purity standards (≥ 98.0% HPLC) with minimal impurities, making it highly suitable for professional dermatology cosmetics, including formulations intended for microneedling and intensive epidermal repair.
How does Xi'an Tihealth ensure the quality of this peptide API?
We employ strict chemical synthesis pathways operating under ISO9001:2015 quality management systems. Every batch undergoes comprehensive HPLC testing to verify purity and confirm the absence of excessive free copper and synthetic byproducts before release to cosmetic manufacturers.
Xi'an Tihealth Biotechnology Compliance Statement: Cosmetic-grade raw material API. Formulate within specified pH parameters to maintain biological activity.
Hot Tags: ghk-cu copper tripeptide-1 api | low free copper cosmetic powder | cas 89030-95-5, China ghk-cu copper tripeptide-1 api | low free copper cosmetic powder | cas 89030-95-5 manufacturers, suppliers, factory
You Might Also Like
Send Inquiry