Nonapeptide-1
Product source: Chemical synthesis
Content specification: ≥ 95% (conventional standard) to ≥ 98% (high-purity specification)
CAS number: 158563-45-2
Testing method: HPLC
Active ingredient: Nonapeptide-1
Product mesh: 100 mesh
Product features: White powder, colorless clear liquid
Product Usage: Whitening and Skincare, Repair Products, Makeup Fusion, Special Care
Product packaging: 1kg/bag (aluminum foil bag); 25kg/drum (cardboard drum)
Product storage: Store in a dry, dark environment at a temperature of ≤ 4 ° C to avoid repeated freeze-thaw cycles, and seal tightly after use.
Shelf life: 24 months
Products Description

(9-Peptide-1) Comprehensive description
Nonapeptide-1 developed by Xi'an Tihealth is a synthetic peptide targeting whitening (molecular formula: C ₆₁ H ₈₇ N ₁₅ O ₉ S),
By blocking the α - MSH signaling pathway, precise inhibition of tyrosinase activity is achieved, reducing melanin production.
The product adopts solid phase synthesis process, with purity>99% and excellent stability. It is suitable for essence, face cream and other formulations (recommended addition of 0.001% -0.1%).
With research grade quality as the core, Nonapeptide-1 is committed to providing safe and efficient whitening solutions for brands, helping to promote product innovation and enhance market competitiveness.
Products Advantages

9-Peptide-1
9-Peptide-1 is very popular in the whitening industry because it has a great advantage, like a "miracle tool", which can penetrate deep into the source of melanin production in the skin, occupy the territory of melanocytes, and gradually cause the disappearance of melanocytes in the body. More importantly, it not only makes the areas where your skin has been used fair, but also gives your skin a three in one effect of anti-inflammatory, anti-aging, and moisturizing.
After sunburn in summer, applying it to the sunburned face can cool down the face and provide sun protection.
During sensitive skin injuries, using it can instantly isolate the skin from external erosion and damage.
When staying up late and breaking the face, it can stimulate the absorption of collagen by the skin, making the skin smooth and moisturized!
It can be mixed with foundation make-up cosmetics and lipstick to make you white!
The core competitive advantages of Xi'an Tihealth Nonapeptide-1 are reflected in the following aspects:
| Project | Market Average | Xi'an Tihealth Nonapeptide-1 |
|---|---|---|
| Purity Control | HPLC ≥95%, with short peptide impurities | HPLC ≥99%, dual purification to remove short peptides |
| Solvent Residues | TFA residue <100ppm | TFA residue <50ppm |
| Regulatory Support | Complies with single market (e.g., China or EU) | China-EU dual compliance, export-ready |
| Supply Flexibility | Minimum order: 1kg | 10g trial production, R&D friendly |
| Cost Competitiveness | Relies on imported raw materials, price volatility | Localized supply chain, 20%-30% lower cost |
Products Function
The core efficacy of nonapeptide-1 is as follows:
Whitening and Spot Reduction:
Clinical data shows that after using skincare products containing nonapeptide-1 for about a month, 80% of users experience a brightening of their skin tone and a reduction in pigmentation.
Anti inflammatory and Soothing:
Inhibits the release of inflammatory factors (such as IL-6), relieves redness and itching, especially suitable for repairing sensitive muscles after sun exposure.
Moisturizing and antioxidant:
It can promote the absorption of hyaluronic acid, increase the moisture content of the epidermis, improve dryness and roughness, eliminate free radicals, reduce oxidative damage, and delay aging.
Promote metabolism and repair:
Can accelerate the renewal of stratum corneum cells, fade acne scars and scars. Stimulate collagen synthesis, reduce wrinkles, and enhance skin firmness.

Products Application

The efficacy and application of Xi'an Tihealth Nonapeptide-1 (nonapeptide-1)
1. Skincare field
Essence/lotion/face cream, suitable for daily skin care formula of whitening and anti-oxidation.
Intensive repair facial mask: Superimposed use can speed up the improvement of pigmentation and skin roughness.
2. Pharmaceutical research and development field
Inhibit the potential activity of inflammatory factors such as TNF - α and IL-6.
Research on the mechanism of antioxidant stress.
3. High end raw material supply
Provide customized formula support for brands, suitable for mid to high end anti-aging lines and medical art post repair products.
Production process diagram

Production Packaging
|
Weight |
Packaging |
Weight |
Packaging |
Weight |
Packaging |
|
1kg |
Aluminum foil bag |
5kg |
Aluminum foil bag |
25kg |
Cardboard bucket |

Payment Methods

Products Delivery methods

Products FAQ

01.What is the whitening principle of Nonapeptide-1?
By blocking the binding of α - MSH (melanocyte stimulating hormone) to receptors, inhibiting tyrosinase activity, reducing melanin synthesis, and improving pigmentation and dullness problems from the source.
02.What is the difference between this ingredient and other whitening ingredients such as niacin and arbutin?
Nonapeptide-1 belongs to targeted signaling pathway inhibitors, with more precise and gentle effects, and less likely to irritate the skin; It can synergistically enhance with other ingredients, but does not require high concentration addition.
03.How to ensure the stability of production batches?
Real time monitoring using HPLC showed that the purity deviation between batches of active ingredients was less than 3%, and heavy metals (lead ≤ 5ppm) and microorganisms (total bacterial count ≤ 1000 CFU/g) strictly met the standards.
04.How long is the shelf life of the product? What are the storage conditions?
The shelf life of the finished powder is 2 years (unopened), and it needs to be sealed in the dark and stored frozen at -20 ℃; It is recommended to use the liquid raw materials after compounding within 6 months.
05.Can it be used for sensitive muscle products?
Experiments have shown that it is mild and non irritating, but it is recommended to conduct patch testing during formula development, especially for sensitive skin populations.
06.What is the purity and stability of the product?
Adopting solid-phase synthesis process, purity ≥ 99%, stable at room temperature, it is recommended to store at -20 ℃ in the dark to prolong activity.
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