Ziziphi Spinosae Semen Extract Liquid
Plant Source：Dried mature seeds of Spiny Jujube Seed
Content Specification：Total Flavonoids ≥3.0%
Detection Method：HPLC
Active Ingredients：Jujubosides, Flavonoids, Polysaccharides, etc.
Appearance：Light brown to dark brown clear liquid with characteristic herbal aroma of Ziziphi Spinosae
Product Uses：
Healthcare & Pharmaceuticals：Used in sleep-aid supplements and anxiety-relief products; serves as a raw material for TCM formulations targeting insomnia and neurasthenia.
Cosmetics：Added to skincare products (serums, sleeping masks) for antioxidant and skin-soothing effects, improving fatigue-induced dullness.
Functional Foods：Incorporated into beverages and dietary supplements for stress regulation and mental wellness.
Product Packaging：1KG/aluminum foil bag; 25KG/cardboard drum (Custom packaging available)
Storage：Store in a cool, dry place, away from direct sunlight and high temperature (≤25°C, ≤60% humidity)
Shelf Life：24 months
Products Description
The best jujube kernel extraction liquid is available at China Tihealth
Our Ziziphi Spinosae Semen Extract Liquid is derived from pure natural Ziziphus jujuba var. spinosa seeds, utilizing advanced extraction technology to retain core plant active ingredients (e.g., spinosin, jujuboside, flavonoids, and polysaccharides).
This concentrated extract delivers pure herbal essence, embodying the natural vitality of Ziziphi Spinosae seeds-perfect for health and wellness applications, as well as skincare formulations seeking tranquilizing and nourishing benefits.
Products Advantages
|
Classification |
Advantage |
Specific Content |
|
Ziziphi Spinosae Semen Extract |
Enrichment of high-purity active ingredients |
Precision purification preserves jujuboside, and flavonoids, ensuring potent biological activity. |
|
Traditional wellness & skincare benefits |
In healthcare, it supports sleep quality, reduces anxiety, and improves mental fatigue. In skincare, it soothes sensitive skin, enhances hydration, and promotes a balanced complexion. |
|
|
Gentle, natural formulation |
Sourced from sustainably harvested Ziziphus jujuba var. spinosa seeds, free from artificial preservatives, synthetic fragrances, and pesticides. Suitable for sensitive skin and dietary supplements. |
Enterprise advantage
| Classification | Advantage | Specific Content |
|
Advantages of Tihealth Company |
Exhibit robust professional R&D capabilities | A seasoned R&D team comprising senior botanists, biochemists, pharmacists, and multi-disciplinary experts is committed to advanced research in plant extracts. The team fosters collaborative industry-academia-research partnerships with renowned scientific institutions and professional organizations, driving continuous process enhancements and formula innovations. |
| Reliable guarantees derive from our modern and advanced production processes | Utilize state-of-the-art equipment globally recognized for excellence, including ultrasonic extraction, low-temperature concentration, and membrane separation technologies. | |
| Rigorous quality control of high-quality raw materials at the source | Maintain long-standing partnerships with premium-quality Ziziphus jujuba var. spinosa planting bases situated in ecologically pristine, pollution-free regions. These bases adhere to strict organic cultivation practices, having implemented a comprehensive raw material traceability system that ensures end-to-end transparency throughout the supply chain. | |
|
Customized and considerate service |
We deliver comprehensive tailored solutions for clients across industries such as pharmaceuticals and health products, encompassing ingredient formulation, dosage form development, and packaging customization. A dedicated professional team oversees the entire process to ensure seamless alignment with market demands and regulatory requirements. |
Products COA
Certificate of Analysis
|
Product Name: |
Ziziphi Spinosae Semen Extract Liquid |
Plant Origin: |
Ziziphus jujuba var.spinosa Seeds |
|
Batch #: |
TH-20241101 |
Part Used: |
Seeds Extract |
|
Representative QTY: |
1000Kg |
Produce date: |
2024-11-01 |
|
Analysis Date: |
2024-12-1 |
Report Date: |
2024-12-2 |
|
ITEM |
SPECIFICATION |
RESULT |
|
Description: Content Pesticides Total Solids |
Light brown clear liquid Negative 3.0% |
Complies Complies 3.25% |
|
Identification Color Reaction |
Positive Reaction for spinosin |
Complies |
|
Tests: Heavy metal Pb As Hg Pesticides Appearance Color PH Odor Total Plate Yeast & Mold Salmonella E.Coli |
≤10ppm |
corresponding |
Products Function
Accurate summary of the core benefits of Ziziphi Spinosae Semen Extract Liquid:
1. Has sedative and hypnotic effects (which is also the core efficacy of jujube seed extract liquid)
◆Activate GABA<sub>A</sub>receptors, enhance chloride ion influx, and inhibit neuronal excitability
◆Downregulate glutamatergic neurotransmission and prolong slow wave sleep (NREM) duration
2. Anti anxiety and antidepressant effects
◆Mainly inhibits monoamine oxidase (MAO-B) and increases levels of 5-HT and dopamine
◆Regulating the HPA axis to reduce cortisol concentration.
3. Prevention of cardiovascular diseases
| Efficacy | Targets | Biomarker Changes |
|---|---|---|
| Anti-arrhythmic | Blocks Na<sup>+</sup>/Ca<sup>2+</sup> channels → ↑ ERP | QT interval ↑15%, VF threshold ↑30% |
| Antihypertensive | Inhibits ACE → ↓ Angiotensin II | Plasma Ang-II ↓25% |
| Anti-atherosclerotic | Reduces LDL oxidation | ox-LDL ↓18%, plaque area ↓22% |
4. Can regulate human immune function
5. Antioxidant effect, the function of eliminating free radicals in the body
6. It also has a protective effect on the human liver and brain nerves
Efficacy Boundaries & Contraindications
| Efficacy Type | Safe Dosage Window | Contraindications |
|---|---|---|
| Sedative-Hypnotic | 50–200mg saponins/day | With barbiturates (↑ respiratory depression risk) |
| Antihypertensive | SBP reduction ≤15mmHg | Hypotensive patients (SBP <90mmHg) |
| Immunomodulation | Polysaccharides ≤300mg/day | Active autoimmune diseases |
Basic efficacy of extracting liquid from sour jujube kernels
| Active Compounds | Content Range | Primary Efficacy |
|---|---|---|
| Spinosin | 0.8–1.2% | Sedative-hypnotic, anxiolytic (core) |
| Jujubosides A/B | 0.5–0.9% | Anti-arrhythmic, neuroprotective |
| Flavonoids (e.g., spinosin) | 2.1–3.4% | Antioxidant, anti-inflammatory |
| Alkaloids (e.g., nuciferine) | 0.15–0.3% | Anti-arrhythmic |
Products Application
Ziziphi Spinosae Semen Extract Liquid has been widely used in various modern industrial fields due to its sedative and sedative pharmacological effects.
Health product field
1. Due to its sedative and calming effects, jujube seed extract is a core component in treating insomnia and anxiety.
2. The ethanol extract of jujube seed can antagonize the arrhythmia induced by aconitine and barium chloride, and lower blood pressure and blood lipids.
3. Jujube seed polysaccharides can enhance humoral and cellular immune functions, making them suitable for immunocompromised individuals.
Food and beverage industry
1. Suanzaoren extract is widely added to functional beverages such as sleep aid drinks and calming tea drinks
2. A health food that is added in liquid form to oral liquids and nutritional supplements to meet the consumption of "medicinal food homology"
Cosmetics and personal care field
1. Anti aging and Soothing Skincare Products
The flavonoids in sour jujube kernels have antioxidant and anti-inflammatory properties, which can repair the skin barrier and relieve sensitive skin. They are used in anti-aging and soothing skincare products.
2. Its sedative properties are used in anti hair loss shampoo, scalp essence, relieving stress hair loss and other scalp care products
Other emerging applications
Veterinary drugs and pet healthcare are used as sedatives and anti anxiety chewable tablets for pets to alleviate separation anxiety
Feed additives improve livestock and poultry stress response and increase survival rate in the breeding industry
📊 Main Application Fields
| Application Field | Specific Forms | Core Functions |
|---|---|---|
| Pharmaceutical Preparations | Oral liquids, Capsules | Sedative-hypnotic, Anti-arrhythmic |
| Functional Food/Beverages | Herbal teas, Paste formulations, GABA-compound drinks | Sleep improvement, Anti-anxiety |
| Skincare Products | Essences, Masks | Anti-inflammatory & antioxidant, Soothing & repair |
| Pet Healthcare | Chewable tablets, Calming sprays | Alleviating pet stress responses |
Production process diagram
Raw Material Collection (Ziziphi Spinosae Seeds) → Low-Temperature Pulverization → Ultrasonic Extraction → Filtration & Chromatography Purification → Vacuum Concentration → Quality Testing (COA Compliance) → Sterile Packaging → Global Distribution
Production OEM
The OEM services provided by Xi'an Tihealth Biotechnology Co., Ltd. have significant advantages
Customized Formulation: Adjust extract potency (polysaccharides/triterpenoids), solubility, and dosage form (liquid, powder, capsules).
Quality Control: GMP-certified facilities, third-party lab testing for each batch (COA provided).
Brand Confidentiality: White-label solutions with secure IP protection.
Production Packaging
Payment Methods
Delivery methods
As a biotechnology company, Tihealth Biotechnology Company provides international cross-border e-commerce logistics services with the following characteristics:
1. International express delivery services
2. Dedicated logistics services
3. Support dual clearing service
Products FAQ
Ziziphi Spinosae Semen Extract Liquid FAQ
Is your Ziziphi Spinosae Semen Extract Liquid safe for long-term use?
How does the extract promote sleep?
Can this extract be used in oil-based cosmetic formulations?
What is the shelf life and storage advice?
How to verify the authenticity of active ingredients?
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