Nonapeptide Powder

The unique advantages of nonapeptide can be summarized as follows:

Whitening and brightening: By competitively blocking receptors on melanocytes, reducing melanin production, and achieving even and brightening skin tone.

Antioxidant: It has good antioxidant activity and can alleviate UV-A-induced oxidative stress.

Promote collagen synthesis: Stimulate the synthesis of collagen in the skin, enhance skin elasticity and firmness.

Anti aging: increases skin moisture, improves skin elasticity, and delays the aging process.

Blocking the mTOR pathway: It has a good skin photoprotective effect and can repair damaged skin.

Efficient purification technology: using high-performance liquid chromatography to purify and improve product purity and safety.

High biological activity: Simulating natural processes within living organisms, it has stronger targeting and efficacy.

These advantages make nonapeptide significantly competitive in skincare and medical applications.

The function and application of nine peptides can be described in detail from the following aspects:

1. Inhibition of Melanogenesis:
Jiupeptide-1 is a small molecule biomimetic peptide that competitively blocks receptors on melanocytes, preventing the binding of melanocyte stimulating hormone (MSH) to MC1 receptors, thereby inhibiting tyrosinase activity and reducing melanin production. This mechanism enables nonapeptide-1 to effectively reduce melanin production, achieving whitening and spot lightening effects.

2. Brightening skin tone:
Due to its ability to reduce melanin production, nonapeptide-1 is also commonly used to brighten skin tone and improve uneven skin tone.

3. Scar repair and moisturization:
In addition to whitening and lightening spots, nonapeptide-1 also has the effects of moisturizing and repairing scars, which can help improve dry skin problems.

4. Antioxidant and anti-aging:
Nine peptide-1 has a certain antioxidant capacity, which can prevent skin aging, restore skin elasticity, and repair fine lines.

 

 

 

 

The function and application of nine peptides can be described in detail from the following aspects:

Beauty and skincare products

Nine peptide-1 is widely used in beauty and skincare products such as whitening, lightening spots, and brightening skin tone. For example, it can be added to skin care products such as cream, essence and facial mask to help improve skin color and fade spots.

Injection beauty

In some high-end beauty projects, nonapeptide-1 can directly act on the skin through injection to achieve the effect of delaying aging and brightening skin tone.

Research on cosmetic formula

Studies have shown that cosmetics containing nonapeptide-1 can significantly improve skin tone brightness and reduce pigmentation after use.

Anti tumor research

Some nine peptides have also been studied for use in the field of anti-tumor, such as certain specific sequences of nine peptides that can inhibit the proliferation of leukemia cells and induce tumor necrosis.

Jiupeptide-1 not only has wide applications in the field of beauty and skincare, but also shows potential in anti-aging and anti-tumor research. Its main function is to whiten and lighten spots by inhibiting melanin production, and it has various effects such as scar repair, moisturizing, and antioxidant.

The production method of nine peptides mainly involves two technical pathways: solid-phase synthesis and liquid-phase synthesis. The following is a detailed description of the production process:
1. Solid phase synthesis method:
Resin connection: Firstly, the carboxyl terminal amino acid of the peptide to be synthesized is reacted with chloromethylpolystyrene resin and covalently connected to the resin.
Deprotection and condensation: Next, remove the terminal protecting group of the first amino acid and use DCC (dicyclohexylcarbode) as a condensing agent to attach the second amino acid to the amino group of the first amino acid. Repeat the above steps to control the sequential elongation of peptide chains.
Cracking and purification: The final step is to suspend the resin in anhydrous trifluoroacetic acid, introduce dry HBr to detach the peptide from the resin, and remove some protective groups. The entire synthesis process can be carried out on a program-controlled automated solid-phase peptide synthesizer.

2. Liquid phase synthesis method:
Condensation reaction: In liquid-phase synthesis, each step of the condensation product can remove by-products through crystallization or washing processes, resulting in higher product quality, but time-consuming and complicated procedures.
Purification steps: Liquid phase synthesis typically involves multiple purification processes, such as using HPLC (high-performance liquid chromatography) for purification to ensure high purity of the final product.

Both methods have their own advantages and disadvantages. Solid phase synthesis method is suitable for large-scale production and has a high degree of automation, but requires specific equipment and resins; The liquid-phase synthesis method can provide higher product quality, but it is costly and time-consuming.

In addition, there may be other technical details and steps that may be adopted in specific production processes, such as using specific solvents and protective groups to optimize the synthesis process.