Bio-Fermented N-Acetylneuraminic Acid (Sialic Acid 98%) | Neu5Ac API | CAS 131-48-6
N-Acetylneuraminic Acid (Neu5Ac / Sialic Acid)
Ultra-High Purity ≥98% | Bio-Fermented | The Ultimate Cognitive & Anti-Aging Carbohydrate
Xi'an Tihealth is a premier manufacturer of ultra-high purity N-Acetylneuraminic Acid (CAS 131-48-6), widely recognized in the industry as Sialic Acid or "Bird's Nest Acid." Naturally found in high concentrations within human colostrum and edible bird's nests, Neu5Ac is a critical signaling carbohydrate that orchestrates neurodevelopment, immune modulation, and cellular youth.
Moving beyond traditional, unsustainable extraction methods prone to avian contaminants, our Neu5Ac is synthesized via a proprietary advanced bio-fermentation process. This yields a ≥ 98.0% purity active ingredient that is 100% Vegan, non-GMO, and completely free from animal-derived pathogens. It serves as the gold standard for infant formula fortification (mimicking HMOs), premium Nutricosmetics, and advanced cognitive-support nutraceuticals.
Formulation & Stability Profile
Formulators require ingredients that do not disrupt manufacturing processes. Our Neu5Ac is engineered for seamless integration across diverse matrixes:
Excellent Solubility
Highly soluble in water (>50g / 100ml at 20°C). Forms a crystal-clear, colorless solution, making it perfect for transparent RTD beverages and liquid collagen vials.
Thermal & pH Stability
Exhibits robust thermal stability. Easily survives standard pasteurization and UHT (e.g., 135°C for 3s). Stable across a broad pH range (pH 3.0 - 7.0).
Organoleptic Profile
Virtually odorless with a clean, slightly acidic taste. It requires zero masking agents, preserving the intended flavor profile of your finished functional food or syrup.
Clinical Mechanism of Action
1. Synaptic Plasticity: The building block of brain gangliosides. Enhances neurotransmission velocity and learning capacity.
2. Pathogen "Decoy" Receptor: Exogenous Neu5Ac competitively binds to viral/bacterial pathogens in mucosal linings, physically preventing them from adhering to host cells.
3. Anti-Melanogenesis: Competitively inhibits tyrosinase activity, downregulating melanin production for systemic skin brightening.
Core Application Matrix
- Infant Formula: Replicates Human Milk Oligosaccharides (HMOs) for brain development and immunity.
- Nutricosmetics: Premium additive for "Beauty-from-Within" liquid collagen and whitening capsules.
- Immune Syrups: Non-stimulant mucosal immune defense agent for pediatric gummies.
- Geriatric Care: Delays cognitive decline and supports brain barrier integrity in seniors.
Strict Certificate of Analysis (≥98% Standard)
| Test Parameter | Acceptance Criteria | Methodology |
|---|---|---|
| Purity (Assay) | ≥ 98.0% | HPLC-ELSD |
| Appearance | White to off-white powder | Visual |
| Specific Rotation [a]D20 | -30.0° to -34.0° | Polarimetry |
| Loss on Drying | ≤ 2.0% | CP2020 / USP |
| Heavy Metals (Total) | ≤ 10.0 ppm | ICP-MS |
Quality Assurance & Technical FAQ
Ready to formulate with premium Bio-Fermented Sialic Acid?
Partner with Xi'an Tihealth for stable supply chain capacity, GMP-compliant manufacturing, and full regulatory documentation.
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