Pharmaceutical-Grade Deep-Sea Salmon PDRN (DNA Sodium) Powder

Pharmaceutical-Grade Deep-Sea Salmon PDRN (DNA Sodium) Powder

Product Name: DNA Sodium (PDRN, Polydeoxyribonucleotide)
Source: Deep-Sea Salmon (different from ordinary deep-sea trout)
Assay Standard: ≥ 99.0%
Extraction Part: Salmon milt / sperm sacs
Molecular Weight Fragments: 80–100bp, 200–250bp
Protein Impurity Limit: ≤ 1.0%
Stability Performance:
Stored at 2–8℃: No activity loss within 36 months
Stored at room temperature: Almost no activity loss within 12 months
Storage Condition: Refrigerate at 2–8℃
Shelf Life: 24 Months
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PDRN 2

Deep-Sea Salmon PDRN (DNA Sodium)

Xi'an Tihealth - The "Liquid Gold" of Medical Aesthetics & Tissue Repair

Assay ≥ 99.0% Protein ≤ 1.0% Deep-Sea Salmon Sourced

Officially registered under the INCI name DNA Sodium, Polydeoxyribonucleotide (PDRN) is a highly refined macromolecule essential for advanced tissue repair and dermatological formulations. This specific DNA fragment is extracted exclusively from the sperm sacs of Deep-Sea Salmon, a raw material distinctly differentiated from standard oceanic salmon or trout species.

Our proprietary isolation process-encompassing enzymatic cleavage, depurination, precipitation, and chromatography-yields a superior white or off-white to pale yellow powder, particles, with no visible impurities or discoloration. With its protein content strictly limited to not more than 1.0%, Xi'an Tihealth's PDRN guarantees an ultra-pure matrix with zero immunogenicity. It eliminates the risk of nodule formation associated with lesser extracts, serving as the premier API for Class II/III medical devices and clinical-grade cosmetics.

 

API Technical Data Sheet (TDS)

 

Analytical Parameter Strict Specification Limit
Product Name DNA Sodium (PDRN) 
Biological Source Deep-Sea Salmon Milt (Distinct from standard Salmon/Trout)
Physical Appearance White or off-white to pale yellow powder, particles
Assay (Content) Not Less Than (NLT) 99.0% 
Protein Content Not More Than (NMT) 1.0% 
Phosphorus Content 8.4% - 9.3% (Calculated on the dried basis)
Loss on Drying NMT 7.0% 
Heavy Metals Arsenic ≤ 0.2mg/kg; Cadmium ≤ 0.1mg/kg; Mercury ≤ 0.1mg/kg; Lead ≤ 2mg/kg
Microbial Limits (TAMC) NMT 1000cfu/g

 

Mechanisms of Cellular Regeneration

 

Cellular Microenvironment Activator

Operating as a potent cell growth activator, PDRN fundamentally alters the cellular microenvironment rather than merely masking superficial symptoms. It exhibits profound capabilities in promoting ischemic resistance and accelerating structural tissue repair.

Anti-Inflammatory Mediation

Beyond structural repair, PDRN acts as a proven therapeutic adjunct in managing complex inflammatory cascades. In advanced dermatological research, it effectively addresses persistent inflammatory skin conditions while ensuring biological compatibility.

Dermal Anti-Aging Matrix

For premium medical aesthetics, PDRN is a formidable anti-aging agent. It actively reverses the chronological skin aging process, mitigates the loss of subcutaneous collagen, controls facial erythema, and downregulates hyperpigmentation.

 

Practical Formulation Guidelines

 

1. Daily Skincare & Barrier Integration

PDRN is highly compatible with single-dose serums and barrier creams. We recommend formulators adopt a "morning protection (PDRN) + evening repair (regenerative factors)" protocol. This synergy fortifies the epidermal barrier and is perfectly suited for sensitive skin without requiring a tolerance-building phase.

Daily Skincare Barrier Integration

2. Targeted Acne Management Protocols

In acne protocols, utilizing PDRN ampoules immediately following mild chemical exfoliation dramatically enhances the transdermal absorption of active constituents. Layering this with a regenerative barrier cream definitively suppresses local inflammation while restoring elasticity and natural skin radiance.

Targeted Acne Management Protocols

 

 

Logistics & Storage Integrity

Ensuring Maximum Biological Activity

 

Stability is the hallmark of a premium biological raw material. To guarantee the highest efficacy, the product must be kept refrigerated. Under these controlled conditions, the active DNA fragments remain completely stable, preserving the integrity of the macromolecule for downstream formulation.

 

Formulation & Procurement FAQ

Q1: Is PDRN suitable for high-end cosmetic manufacturing and medical devices?

Absolutely. Due to our rigorous purification process-which ensures the protein content is not more than 1.0%-our PDRN exhibits zero immunogenicity, making it safe and ideal for premium cosmetics and Class II/III medical devices.

Q2: How does Deep-Sea Salmon PDRN differ from standard salmon or trout extracts?

Our API is specifically extracted from the sperm sacs of Deep-Sea Salmon, representing a distinctly differentiated biological source compared to standard oceanic chum or trout. This specific lineage provides an optimal base sequence structure that closely mimics human DNA, maximizing cellular compatibility and efficacy.

Q3: How is the purity of your DNA Sodium scientifically guaranteed?

Every batch is subjected to rigorous analytical testing. Our specifications demand an assay of not less than 99.0%, strict control of phosphorus content (8.4% - 9.3%), alongside tight limits for heavy metals (e.g., Lead ≤ 2mg/kg) and microbiological safety (TAMC NMT 1000cfu/g).

 

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